NEET PG 2022 Question Paper Biochemistry

NEET PG 2022
Question Paper
Biochemistry
(Based on Memory Recall)
Q1. The following histological image is seen in the patient who is complaining of growth failure
and abdominal distension. Signs found were anemia, thrombocytopenia & bony pain. Which
enzyme is deficient in this patient?

a. Beta Glucocerebrosidase
b. Sphingomyelinase
c. Glu 6 phosphate
c. Hexosaminidase

Q2. DNA packing is done by?
a. Histone
b. Glycoprotein
c. Nucleic acid
d. Helicases
e. Cytochromes

Q3. A paint factory worker working since 20 years c/o joint pain, insomnia, fatigue,
constipation, headache. He is found to have anemia. Enzyme affected is?
a. Uroporphyrinogen Ill synthase
b. Uroporphyrinogen I synthase
c. ALA synthase
d. Ferrachelatase

Q4. Complex 4 inhibitor ?
a. Cyanide

b. Carbon Dioxide
c. Oligomyein
d. Antimycin

Q5. Enzyme defect in McArdle’s Disease?
a. Myophosphorylase
b. Glucose. 6 phosphatase
c. Glycogen phosphorylase
d. Hexokinase

Q6. An Alcoholic patient on anti-tubercular drugs for the past 3 months complains of
numbness, tingling and burning sensation in all the extremities. What could be vitamin
deficiency?
a. Vitamin A
b. Vitamin B12
c. Vitamin B1
d. Vitamin D

Q8. A known patient of Tuberculosis, on INH for the past 3 months complains of
numbness, tingling and burning sensation in all the extremities. What could be the
vitamin deficiency?
a. Vitamin B6
b. Vitamin B12
c. Vitamin B1
d. Vitamin B3

Q9. Cherry Red spots on retina and mental retardation is seen in:

a. Gaucher's disease

b. Tay Sach’s disease
c. Hunter syndrome

d. Krabbe’s disease

Q10. FAD status in body is determined by?
a. Thiamine
b. Glutathione reductase
c. Hexokinase
d. Transketolase

Q11. True about Warburg effect?
a. Makes cancer cells immortal
b. Aerobic glycolysis with lactate formation
c. Produces more ATP
d. Decrease glucose uptake

Q12. A Mediterranean person didn’t receive primaquine. Which pathway is affected by
G-6-PD enzyme deficiency ?
a. HMP pathway
b. Glycolysis
c. Gluconeogenesis
d. Kreb cycle

Q13. True about telomeres and telomerase is :
a. Increased telomere length with ageing
b. Gradually decreasing length of telomeres with ageing
c. Telomeres have coding sequences
d. Telomerase is found in somatic cells

Q14. When a codon is changed to a stop codon, then it is:
a. Stop codon mutation
b. Non sense mutation
c. Mis sense mutation
d. Silent mutation

Q15. Condition shown below is due to which Vitamin deficiency?

a. Vitamin A
b. Vitamin B
a. Vitamin C
a. Vitamin D

Q16. Rice water diarrhoea, intoxication is due to which ganglioside?
a. GM-1 ganglioside receptor
b. GM 2 ganglioside receptor
c. GM 3 ganglioside receptor
d. GD 1alpha ganglioside receptor

Q17. Mechanism of action of botulinum toxin is:
a. Inhibits NM receptor
b. Inhibits reuptake of Acetyl Choline
c. Inhibits release of Acetyl Choline from lower motor neurons
d. Inhibits synthesis of Acetyl Choline

Q18. Fatty acid transport through mitrochondrial membrane is via?
a. Carnitine
b. Acylcarrier protein
Cholesterol transporter
d. LCAT

Q19. A woman on anti-depressants presents with bleeding. She gives a history of bulky
stools which stick to the pan. Which of the following vitamin deficiency can cause
bleeding in this condition?
a. Vitamin A
b. Vitamin D
c. Vitamin E
d. Vitamin K

Q20. ldentify the acid-base disorder in a patient with the follows
pH - 7.2

pco2 - 80 mm Hg
a. Metabolic acidosis
b. Metabolic alkalosis
c. Respiratory acidosis
d. Respiratory alkalosis

Q21. Which of the following has ‘Autosomal Recesive pattern of inheritance?
a. Achondroplasia
b. Huntington's disease
c. Cystic fibrosis
d. Familial hypercholesteroleniia