NEET PG 2022 Question Paper Pharmacology

NEET PG 2022
Question Paper
Pharmacology
(Based on Memory Recall)
Q1. A patient was given intravenous botulinum toxin and the patient died. Mechanism of
botulinum toxin overdose is
a. Inhibits release of acetylcholine
b. Inhibit reuptake of nor-epinephrine
c. Blockade of post synaptic nicotinic cholinergic receptors
d. Inhibit entry of acetylcholine in vesicle

Q2. Drug of choice in paracetamol overdose is
a. N-acetylcysteine
b. Dopamine
c. Hydralazine
d. Furosemide

Q3. A young female presented with left sided severe throbbing headache associated with
nausea, vomiting, photophobia and phonophobia. Which of the following drug can
provide immediate relief to this patient?
a. Propranolol
b. Sumatriptan
c. Topiramate
d. Flunarizine

Q4. A patient on digoxin therapy accidently consumed 8 tablets of digoxin 0.25 mg. Two
hours later, he presented to emergency with heart rate of 54 bpm and ECG evidence of
third-degree AV block. What is the immediate management of this patient?
a. Digoxin immune Fab
b. Lignocaine
c. Phenytoin
d. DC cardioversion

Q5. An 82 year old patient presented with acute episode of breathlessness. Chest X ray

shows pulmonary edema. History reveals that the patient has uncontrolled hypertension
and is not taking the medication regularly. Which should be the management of this
patient?

a. Intravenous nitroglycerine
b. Salbutamol nebulization
c. Intravenous salbutamol
d. Intravenous antibiotics plus oxygen

Q6. Which of the following hypolipidemic drug acts by inhibition of PCSK-9?
a. Atorvastatin
b. Evolocumab
c. Ezetimibe
d. Lomitapide

Q7. A patient presents with pituitary tumor that overproduces growth hormone. surgical
removal of the tumor was incomplete. What is the first line treatment of this patient?
a. Leuprolide
b. Octreotide
c. Nafarelin
d. Goserelin

Q8. A 40 year old male presents with protrusion of chin, excessive sweating, impaired
glucose tolerance and enlargement of hands and feet? Which of the following drugs is a
growth hormone receptor antagonist used to treat this condition?
a. Pegvisomant
b. Octreotide
c. Cabergoline
d. Olcegepant

Q9. A 40-year-old diabetic female presented to emergency with abdominal pain, vomiting
and recent onset confusion. On examination, she had irregular breathing and
dehydration. Her blood sugar is 539 mg/dl and there was presence of ketone bodies in
the urine. Blood pressure of the patient is 80/50 mm Hg. What is the next best step in the
management of this patient?
a. Regular insulin
b. Intravenous fluids
c. Intravenous fluids with regular insulin
d. Long acting insulin

Q10. A female presented with galactorrhea. Her urine pregnancy test was negative. MRI
of head revealed a large pituitary tumor. Patient refused to undergo surgery for the
tumor. Which of the following is the best drug for the treatment of this patient?
a. Octreotide
b. Bromocriptine
c. Promethazine

d. Clozapine

Q11. A patient with opioid poisoning presents with severe respiratory depression. What
is the most effective drug for treatment of this patient?
a. Fomepizole
b. Naltrexone
c. Flumazenil
d. Naloxone

12. A patient on anti-depressant therapy presents with elevated body temperature, dilated
pupil, palpitations and low blood pressure. ECG shows tachycardia, broad QRS complex
and right axis deviation. Which of the following interventions must be done immediately?
a. Wait and watch
b. Intravenous sodium bicarbonate
c. Intravenous esmolol
d. DC cardioversion

Q13. A patient presents with tremors, rigidity and bradykinesia. Which of the following
drugs can be used for the treatment of this patient?
a. Selegiline
b. Donepezil p at k
c. Fluoxetine
d. Haloperidol

Q14. A child born by normal vaginal delivery developed repeated attacks of flexion of
neck over the trunk and jerks in the hands. EEG shows the presence of hypsarrhythmia.
Anti-epileptic drug of choice for this patient is?
a. Phenobarbitone
b. Phenytoin
c. ACTH
d. Levetiracetam

Q15. An 11-year-old boy presented to emergency with vomiting. Parents gave history of
consuming 10-15 tablets of ferrous sulphate a day before. What is the antidote of iron for
treatment of this patient?
a. Dimercaprol
b. Desferrioxamine
c. d- Penicillamine

d. Activated charcoal

Q16. A deep vein thrombo: tient was started on an anticoagulant therapy. Gext day) the
patient presented with the features shown in the diagram below. Likely drug implicated
for this adverse effect is

a. Heparin
b. Rivaroxaban
c. Warfarin
d. Dabigatran

Q17. A patient with COPD was given intravenous aminophylline erapy following which
the patient developed re: This is due to action on which effector?
a. Adenosine receptors
b. Beta 2 adrenergic receptors
c. IL-10
d. Histone deacetylase

Q18. A female with ovarian cancer was on cisplatin therapy. He presented to hospital with
several episodes of vomiting. After giving an antiemetic drug, the patient developed
dystonia. The anti-emetic drug most likely to be responsible for these features is
a.Metoclopramide
b.Meclizine
c. Ondansetron
d.Scopolamine

Q19. A pregnant female with urinary tract infection took antimicrobials for the same. The

baby of this female developed tendon rupture and arthropathy. What is the likely
mechanism of action of the antimicrobial consumed by the pregnant female?
a. Folic acid synthesis inhibitor

b. Mycolic acid synthesis inhibitor
c. DNA gyrase inhibitor
d. DNA inhibitor

Q20. A 48 year old patient presented to OPD with tingling and numbness of fingers. The
patient is chronic alcoholic and was recently started on antitubercular treatment. What
should be the treatment of this patient?
a. Vitamin B3
b. Vitamin B6
c. Vitamin B1
d. Vitamin B12

Q21. In MDR tuberculosis, which of the following drug combinations show resistance?
a. Rifampicin and Fluoroquinolones
b. Isoniazid and rifampicin
c. Isoniazid and Pyrazinamide
d. Rifampicin and kanamycin

Q22. A patient presented with hyperkalemia. Which of the following drugs can cause
intracellular movement of and thus decrease in extracellular potassium levels?
a. Atropine
b. Lactic acid
c. Epinephrine
d. Glucagon

Q23. Which of the following drugs have least adverse effect on pleura?
a. Bromocriptine
b. Metformin
c. Nitrofurantoin
d. Methysergide