GNDU 2020 Entrance Exam Question Paper M.Sc Biotechnology

Set Id : 60866_7 GNDU - M Sc Biotechnology

Section 1 - M Sc - Biotechnology

1) For generating single stranded clones which of the vectors will be used

A) Cosmid

B) phagemid

C) Lambda gt10

D) Lambda gt11

2) Antibodies are

A) produced by Bacteria

B) Both A and B

C) proteins

D) None of the above

3) The formula for conversion of temperature between Degree Fahrenheit 'F' and Degree Celsius 'C' is given by

Considering 'F' as a function of 'C', choose the correct statement regarding the inverse function
F-1

A)

B)

C)

D) F-1 does not exist

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Set Id : 60866_7 GNDU - M Sc Biotechnology

4) Which of following has highest ionization potential?

A) Beta ray

B) All have same

C) Gamma ray

D) Alpha rays

5) A circular coil of ‘n’ turns and radius ‘r’ carries a current ‘I’. The magnetic field at the centre is

A)

B)

C)

D)

6) A wheel makes 360 revolutions in one minute. Through how many radians does it turn in 2 seconds?

A) 60o

B) 2π radians

C) 180o

D) 120o

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Set Id : 60866_7 GNDU - M Sc Biotechnology

7) Match the terms given in the Column I with the units given in the column II.

A) i-(C), ii-(A), iii-(D), iv-(B)

B) i-(D), ii-(C), iii-(B), iv-(A)

C) i-(C), ii-(D), iii-(A), iv-(B)

D) i-(A), ii-(B), iii-(C), iv-(D)

8) Histotypic culture

A) None of the above

B) Mixed lineage cells grown in high density

C) Single lineage grown in high density

D) Primary culture

9) Inulin is a type of

A) Hormone

B) Carbohydrate

C) Enzyme

D) Amino acid

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Set Id : 60866_7 GNDU - M Sc Biotechnology

10) Which of the antigens listed below is likely to be least immunogenic

A) A protein with a molecular weight of 50,000 daltons

B) A protein with a molecular weight of 5,000 daltons

C) BSA in Freund’s incomplete adjuvant

D) BSA in Freund’s complete adjuvant

11) Gamma rays are

A) Electromagnetic wave

B) Radiation

C) Both A and B

D) None of the above

12) Western blotting is used to detect which of the following

A) RNA

B) DNA

C) Protein

D) Sugars

13) CDRs for antigen binding on antibody are present on

A) None of the above

B) Carboxy terminal of Fc portion

C) Hinge portion of antibody

D) Amino terminal of Fc portion

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Set Id : 60866_7 GNDU - M Sc Biotechnology

14) Which one of the following orders is correct for the bond dissociation enthalpy of halogen molecule?

A) F2 > Cl2 > Br2 > I2

B) Br2 > I2 > F2 > Cl2

C) I2 > Br2 > Cl2 > F2

D) Cl2 > Br2 > F2 > I2

15) Which of the following restriction enzyme cleavage sites would you expect to occur most often in DNA?

A) GC GC

B) AAA TTTA

C) GGG CGCCCC

D) GGG CCC

16) One of the following antibodies is expressed on naïve B Cells

A) IgE

B) IgM

C) IgG

D) IgA

17) Two electric bulbs of 40 watt each are connected in series. The power consumed by the combination will be

A) 60 watt

B) 20 watt

C) 100 watt

D) 80 watt

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Set Id : 60866_7 GNDU - M Sc Biotechnology

18) If you did six cycles of PCR starting with one double stranded DNA template, how many (double-stranded) DNAs
would result?

A) 32

B) 16

C) 62

D) 5

19) The SI unit of conductance is

A) mho

B) mho m-1

C) Ohm

D) ohm-m

20) The negative charge (at neutral pH) on DNA is:

A) On the oxygen atoms at the 3' position on the ribose sugars

B) On the nitrogen atoms in the pyrimidine and purine rings

C) On the oxygen atoms attached to the phosphate groups in the sugar-phosphate backbone

D) On the hydrogen atoms at the 2'-position of deoxy-ribose

21) Torque acting on a magnet held at angle ‘θ’ with a magnetic field is maximum, when θ =

A) 0o

B) 180o

C) 360o

D) 90o

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Set Id : 60866_7 GNDU - M Sc Biotechnology

22) A manufacturer has 600 litres of a 12% solution of acid. How many litres of a 30% acid solution must be added to it
so that the acid content in the resulting mixture is between 15% and 18%?

A) Between 120-300 litres

B) Between 300-420 litres

C) Between 20-30 litres

D) Between 100-120 litres

23) Equation of a straight line perpendicular to the line 2x + 3y = 4 and passing through the point (1,2) is given by

A) 2y - 3x = 1

B) 2x + 3y = 8

C) 2x + 3y = 4

D) 2x - 3y = 4

24) Monoclonal antibodies recognize a single

A) Bacterium

B) Antigen

C) Paratope

D) None of the above

25) Which of the following is most stable in aqueous solution?

A) Ti3+

B) V3+

C) Mn2+

D) Cr3+

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Set Id : 60866_7 GNDU - M Sc Biotechnology

26) For a paramagnetic substance

A) µr = 0

B) µr > 1

C) µr = infinity

D) µr = 1

27) The half-life period of first order reaction is 1386 seconds. The specific rate constant of the reaction is

A) 5.0 x10-2 s-1

B) 5.0 x10-3 s-1

C) 0.5 x10-3 s-1

D) 0.5 x10-2 s-1

28) Lymphoid lineage does not give rise to

A) Basophils

B) T cells

C) B cell

D) NK Cells

29) Which of the following is a true statement about a CRYPTIC PLASMID?

A) It is often used as a reporter gene in cloning reactions

B) It renders bacteria resistant to antibiotic

C) It encodes for a toxin

D) Its function is not known

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Set Id : 60866_7 GNDU - M Sc Biotechnology

30) The number of moles of NaCl in 3 liters of 3M solution is

A) 3

B) 9

C) 1

D) 27

31) Active immunity is acquired through which of the following processes?

A) Natural birth

B) Antibodies

C) Drinking colostrum

D) Vaccination

32) Select the correct IUPAC name for:

A) 5 – methyl - 5 - propylheptane

B) 5 – methyl – 5 - ethyloctane

C) 4 – ethyl - 4 - methyloctane

D) 3 – methyl – 3 - propyloctane

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Set Id : 60866_7 GNDU - M Sc Biotechnology

33) Which is favorable for physical adsorption?

A) High T and low P

B) High T and high P

C) T and P do not affect

D) Low T and high P

34) Why don't restriction enzymes cleave bacterial DNA in the strain that make the enzymes?

A) The restriction enzymes are not synthesized until long after foreign DNA enters the cell

B) The bacterial DNA is modified at the restriction sites

C) The restriction enzymes are synthesized in a different cellular compartment than that which contains the genomic
DNA

D) Bacterial DNA repair mechanisms can repair the DNA faster than it can be cut by enzymes

35) Electric potential ‘V’ and electric flux ‘Ф’ are

A) Both vectors

B) Both scalars

C) V is vector, Ф is scalar

D) V is scalar, Ф is vector

36) The sequence of mRNA is 5’AUGCCGG 3’. What will be the sequence of non-coding DNA strand for this sequence

A) 5’TACGGCC3’

B) 5’CCGGCAT3’

C) 5’TACGCCC3’

D) 3’TACGGCC3’

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Set Id : 60866_7 GNDU - M Sc Biotechnology

37) Which of the following is a non-coding RNA

A) snoRNA

B) All of the above

C) rRNA

D) snRNA

38) Mature RBC lacks

A) Both A and B

B) Cell wall

C) Nucleus

D) None of the above

39) If is the arithmetic mean between the positive numbers a and b, then

A) n = 1

B) n = 0

C) n = -1

D) None of the above

40) In a survey of 500 students in a school, 100 were listed as taking guava juice, 150 as taking orange juice, and 75
were listed as taking both guava as well as orange juice. Then the number of students taking neither guava juice nor
orange juice is equal to

A) 175

B) 325

C) 250

D) 225

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Set Id : 60866_7 GNDU - M Sc Biotechnology

41) One of the following Microscopes is essential for Animal Cell Culture

A) Fluorescent Microscope

B) Phase contrast upright microscope

C) Bright field upright microscope

D) Inverted Microscope

42) Which of the following would be preferable for use in cloning very large (200 kb or more) fragments of DNA?

A) BAC

B) Phagemid

C) Plasmid

D) Cosmid

43) Which of the following chemical bond is not present in protein structure

A) Phosphodiester bond

B) Disulfide bond

C) Peptide bond

D) Covalent bond

44) Which of the following is the optimal temperature for DNA synthesis by Taq DNA polymerase in polymerase chain
reaction?

A) 37oC

B) 45oC

C) 72oC

D) 93oC

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Set Id : 60866_7 GNDU - M Sc Biotechnology

45) Percentage of free space in the body centered cubic unit cell is

A) 20%

B) 28%

C) 32%

D) 34%

46) Electric field intensity (E) due to an electric dipole varies with distance (r) of the point from the centre of dipole as

A) E α 1/r

B) E α 1/r4

C) E α 1/r3

D) E α 1/r2

47) Which of the following is not an application of eddy currents?

A) Speedometers

B) Magnetic brakes

C) Induction furnace

D) Transformers

48) Which of the following equipment is not essential to maintain animal cell cultures

A) Laminar Hood

B) Inverted Microscope

C) CO2 Incubator

D) BOD

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Set Id : 60866_7 GNDU - M Sc Biotechnology

49) The force between two parallel current carrying wires is independent of

A) The radii of wires

B) The medium in which they are placed

C) The length of wires

D) Their distance of separation

50) Which of the following will you use for separating the yeast chromosomes

A) 2D electrophoresis

B) Disc electrophoresis

C) Denaturing electrophoresis

D) Pulse field gel electrophoresis

51) Which of the following ore is best concentrated by the froth floatation process?

A) Malachite

B) Magnetic

C) Siderite

D) Galena

52) Which of the following cell type is likely to grow as suspension culture

A) None of the above

B) Glial cells

C) Epithelial cells

D) B-Lymphocytes

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Set Id : 60866_7 GNDU - M Sc Biotechnology

53) 27oC is equal to

A) 78 F

B) 81.6 F

C) 80.6 F

D) 81 F

54) Choose the incorrect statement.

A)

B)

C)

D)

55) Both Plasmodium falciparum and Plasmodium vivax belong to

A) None of the above

B) Both A and B

C) Same genus

D) Same species

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Set Id : 60866_7 GNDU - M Sc Biotechnology

56) If for real number , the number is purely real, then

A)

B)

C)

D)

57) If is equal to

A)

B)

C)

D)

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Set Id : 60866_7 GNDU - M Sc Biotechnology

58) The property that an amino acid can have more than one codon is called

A) Degeneracy

B) Overlapping codon

C) Universality

D) Non overlapping codon

59) The total number of ways in which 4 cards can be chosen from a pack of 52 playing cards such that cards are of the
same colour is

A)

B)

C)

D) None of these

60) Kirchhoff's second law is based on law of conservation

A) Sum of mass and energy

B) Charge

C) Momentum

D) Energy

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Set Id : 60866_7 GNDU - M Sc Biotechnology

Answer keys

Question Paper No: 60866_7

1 B 31 D
2 C 32 C
3 C 33 D
4 D 34 B
5 B 35 B
6 D 36 B
7 A 37 B
8 C 38 A
9 A 39 A
10 B 40 B
11 C 41 D
12 C 42 A
13 A 43 A
14 D 44 C
15 A 45 C
16 B 46 C
17 B 47 D
18 C 48 D
19 A 49 A
20 C 50 D
21 D 51 D
22 A 52 D
23 A 53 C
24 D 54 A
25 D 55 C
26 B 56 A
27 C 57 D
28 A 58 A
29 D 59 A
30 B 60 D

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