PU CET PG 2018 Question Paper MSc_2Yr__NuclearMedicine_

MSc(2Yr)(NuclearMedicine)

1. An exposure of one coulomb per kilogram is equivalent to how many roentgens?
A) 3876 B) 387.6 C) 38.76 D) 3.876

2. To assess background counts using a GM counter, which of the following statistical model is
used?
A) Normal distribution B) Gaussian distribution
C) Poisson distribution D) Poisson and Gaussian distribution

3. Which of the following is used for the synthesis of triiodothyronine?
A) Epinephrine B) Tyrosine C) Glycine D) Histidine

4. Which of the following route is preferred for administration of radiopharmaceuticals for the
purpose of imaging?
A) Intravenous injection B) Intramuscular injection
C) Subcutaneous injection D) Intraperitoneal injection

5. How many protons are present in 99mTc nucleus?
A) 43 B) 42 C) 56 D) 57

6. Which of the following enzyme is used for the oxidation of iodide ions to form iodine atoms
for the synthesis of thyroid hormones?
A) Peroxidase B) Na+, K+, ATPase
C) Iodothyronine 5’deiodinase D) Catalase

7. One J/Kg corresponds to how many Gray, the unit of radiation dose?
A) 0.1 B) 1 C) 10 D) 100

8. Antiparticle of positron is
A) Neutrino B) Electron C) Antiproton D) Antineutron

9. Which of the following is the conséquence of stochastic effects of radiations ?
A) Cancer B) Splenomegaly C) Cataract D) Sterility

10. RadioIodine-131 atoms upon disintegration emit which of the following radiations?
A) Gamma B) Beta C) Alpha D) Both Gamma and beta

11. How many MBq of radioactivity would be equivalent to 90 micro curie?
A) 0.33 B) 3.33 C) 33.3 D) 333

12. Thermal neutrons have kinetic energy close to
A) 2.5 keV B) 0.25 keV C) 0.25 eV D) 0.025eV

13. Which of the following radiations are used in Nuclear medicine imaging procedures?
A) X-Rays B) Beta particles C) Gamma Rays D) Electrons

14. In 99Mo/99Tc radionuclide generator, 99mTc radioactivity builds up to a maximu level in how
many hours, after elution?
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A) 6 B) 12 C) 18 D) 24

15. Which of the pharmaceutical is localized in the target organ by capillary blockade?
A) MDP B) DTPA C) MAA D) S-colloids

16. Which of the following mainly produces protein, lactoferrin:
A) Bacteria B) Viruses C) Fungus D) Leukocytes

17. A radioisotope with a 6 hour physical half life and a 3 hour biological half life would have
an effective half life of how many hours?
A) 1 B) 2 C) 3 D) 4

18. Which of the following is released from the nucleus during an electron capture decay ?
A) Neutron B) Beta Particle C) Alpha particle D) Neutrino

19. Which of the following techniques is not used for studying the secondary structures of
proteins?
A) Circular dichroism B) Fluorescence spectroscopy
C) X- ray crystallography D) NMR spectroscopy

20. Nearly what percentage of cardiac output enters the kidneys?
A) 5% B) 15% C) 25% D) 35%

21. Deficiency of which of the following hormone causes Diabetes insipidus?
A) Vasopressin B) Oxytocin C) Insulin D) Aldosterone

22. How much radiation dose in permissible levels can be received by a non radiation worker in
one year?
A) 1 mSv B) 5 mSv C) 10 mSv D) 20 mSv

23. Human population receives nearly how much % of the annual dose from Natural
background radiations?
A) 92 B) 82 C) 72 D) 62

24. Plexiglas should preferably be used in shielding which of the following radionuclide?
A) Tc-99m B) Iodine-131 C) Zn-65 D) P-32

25. How much approximate time in minutes, the solid meal takes to clear from the stomach of a
normal person?
A) 105-120 B) 90-105 C) 75-90 D) 60-75

26. To study conformation of proteins, which of the followings technique is employed?
A) Affinity Chromatography B) Gel Chromatography
C) Circular Dichroism D) Gel Electrophoresis

27. Which of the following cells are associated with humoral immunity?
A) B Cells B) Kupffer cells C) Follicular cells D) T Cells
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28. Blood coagulation requires which of the following ?
A) Zinc B) Potassium C) Calcium D) Selenium

29. Which of the following can induce stress in heart muscle?
A) Guanine B) Glucosamine C) Adenosine D) Cytosine

30. Which of the following is the main structural protein in various connective tissues in
animal bodies?
A) Histones B) Collagen C) Hemoglobin D) Heparin

31. Which of the following does not use Fourier Transformation?
A) Positron emission tomography
B) Single photon emission computed tomography
C) Magnetic resonance imaging
D) Rectilinear Scanner

32. What is the value of SI unit of exposure when expressed in microcoulomb in air?
A) 0.258 B) 2.58 C) 25.8 D) 258

33. β-sheets refer to which structure of protein?
A) Primary structure B) Secondary structure
C) Tertiary structure D) Quaternary structure

34. Which of the following process takes place during Electron capture?
A) An electron is ejected from the nucleus B) An electron combines with a neutron
C) An electron combines with a proton D) A neutron is ejected from the nucleus

35. Principal gamma ray energy of 51Cr is
A) 320 Kev B) 220 Kev C) 120 Kev D) 20 Kev

36. Radioisotope 14C upon disintegration emits which of the following?
A) Gamma rays B) Beta particles C) Positrons D) Auger electrons

37. The System International of units uses which of the following unit for measurement of
radioactivity?
A) Rep B) Becquerel C) Rutherford D) Curie

38. Denatured red blood cells when labeled with a radionuclide can preferentially be used to
locate which of the following?
A Heart B) Hepatocytes C) Spleen D) Bone Marrow

39. The width of DNA molecule when expressed in angstrom, nearly is
A) 5 B) 10 C) 20 D) 40

40. The levels of Thyroxine per deciliter of human blood is close to
A) 4-10 nanogram B) 10-20 nanogram
C) 4-10 microgram D) 40-80 microgram

41. The diameter of platelets is nearly
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A) 0.2-0.4 angstrom B) 2-4 angstrom
C) 0.2-0.4 microns D) 2-4 microns

42. The percentage of eosinophils vis-a-vis other white blood cells is
A) 1-6 B) 6-12 C) 12-18 D) 18-24

43. Practically, how much percent of cardiac output goes to lungs?
A) 115 B) 105 C) 95 D) 85

44. Which of the following enzyme unwinds double helix of DNA ?
A) Topoisomerase B) Gyrase C) Helicase D) Endonuclease

45. Which of the following is close to right answer in case of radioisotope 32P
A) To treat bone pain caused by metastases
B) To treat malignant ascites
C) To treat polycythemic vera
D) To treat polycythemia vera and bone pain caused by metastases

46. Which of the following is reduced to a large extent in Nude mice?
A) B lymphocytes B) T lymphocytes
C) Kupfer cells D) Both B lymphocytes and Kupfer cells

47. Gastric Intrinsic factor is secreted by which of the following cells ?
A) Schwann cells B) Glial Cells C) Parietal Cells D) C-Cells

48. Dry weights of bones are ascribed to nearly what percent of organic matrix?
A) 80 B) 60 C) 30 D) 10

49. Which of the following does not cross blood-brain barrier?
A) Diethylenetriaminepentaacetic acid B) Fluorodpa
C) Fluorodeoxyglucose D) Ethyl cysteinate dimer

50. How much amount of blood plasma is filtered by glomeruli in kidneys per day?
A) 18o ml B) 8 liter C) 8o liter D) 180 liter

51. Principal Gamma ray energy of radioisotope Iodine-123 is
A) 5.9 KeV B) 59 KeV C) 159 KeV D) 1.59 MeV

52. Physical half life of Tl-201 is
A) 73 minutes B) 7.3 hours C) 73 hours D) 7.3 days

53. In double helical DNA, if adenine is 30 percent of the total bases, then cytosine shall be how
much percent?
A) 40 B) 30 C) 20 D) 10

54. Which of the following is not used in Radioimmunoassay?
A) Antigen labelled with radioisotope
B) Antibodies not labelled with radioisotope
C) Antibodies labelled with radioisotope
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D) Antigen not labelled with radioisotope

55. Which type of radiations are emitted by the disintegration of Ga-68
A) Gamma B) Alpha particles C) Beta negative D) positrons

56. Which of the following effect takes place upon interaction of UVB radiations with DNA?
A) Cross linking of purine and pyramidines
B) Deletion of purines
C) Dimerisation of pyramidines
D) Substitution of purine and pyramidines

57. Myelin is synthesized by which of the following cells?
A) Melanocytes B) Myocyte C) Hstocyte D) Schwann

58. Which of the following process is used in the decay of Tc-99m?
A) Isobaric transition B) Internal conversion
C) Auger transition D) Isomeric transition

59. Which of the following xenobiotics shall exhibit maximum bone to muscle uptake?
A) Phytic acid B) Diethylenetriaminepentaacetic acid
C) MDP D) Fluorodeoxyglucose

60. Graves’ disease is caused by which of the following?
A) Antibodies to peroxidise B) Deficiency of peroxidase
C) Antibodies to TSH receptor D) Deficiency of tyrosine iodinase

61. Which bacteria in particular present in GI tract, utilizes 14C labelled urea in breath test?
A) E. Coli B) S. Aureus C) H. Pylori D) S. Enterica

62. What is the maximum annual permissible dose for Gonads of a radiation worker when
expressed in mSv?
A) 25 B) 50 C) 75 D) 100

63. Identify the following process which does not occur in the nucleus of a human cell?
A) Replication B) Transcription C) Repair D) Translation

64. Which of the following radiations emitted from Iodine-131 that kill thyroid follicles during
the treatment of thyroid papillary carcinoma?
A) Gamma radiations B) Alpha particles
C) Beta particles D) Positrons

65. Identify which of the following corresponds to the absorption of a dose of 1 rad?
A) 0.01Gy B) 0.1Gy C) 1.0Gy D) 10Gy

66. Potassium is an analogue of
A) Strontium B) Rubidium C) Selenium D) Technetium

67. Physical half life of Ge-68
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A) 271 min B) 271 hours C) 271 days D) 271 years

68. Mucin- MUC5AC is secreted by which of the following cells?
A) C-Cells B) Goblet C) Crypt D) Fibroblasts

69. Nearly, what percentage of human genome is shared with rat and mouse genomes?
A) 100 B) 90 C) 80 D) 70

70. Calcitonin is secreted by which of the following cells?
A) Microglial cells B) Parafollicular cells
C) Astrocytes D) Follicular cells

71. Nearly how much percent of blood is received by Liver from the portal vein?
A) 90 B) 80 C) 70 D) 60

72. For most medical applications, the frequency of ultrasound waves is in the range:
A) 1-18 Hz B) 1-18 KHz C) 1-18 MHz D) 1-18GHz

73. Identify, which cells respond first to move towards the site of inflammation?
A) Platelets B) Eosinophils C) Lymphocytes D) Neutrophils

74. Which one of the following happens during “Auger effect”?
A) Single vacancy is created in the M shell
B) Single vacancy is created in the L shell
C) Two vacancies are created in either L or M shell
D) Two vacancies are created in both L and M shells

75. Which of the following is produced when there is a fall in arterial blood pressure?
A) TSH B) Relaxin C) Renin D) Cholecystokinin

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