TN 12th Question Paper 2022 Microbiology

No. of Printed Pages : 8
5962
!5962Microbiology! £vÄ Gs
Register Number

PART - III
~sq°›¯À / MICROBIOLOGY
( uªÌ ©ØÖ® B[Q» ÁÈ / Tamil & English Version)

Põ» AÍÄ : 3.00 ©o ÷|µ® ] [ ö©õzu ©v¨ö£sPÒ : 70

Time Allowed : 3.00 Hours ] [ Maximum Marks : 70

AÔÄøµPÒ : (1) AøÚzx ÂÚõUPЮ \›¯õP £vÁõQ EÒÍuõ GߣuøÚ \›£õºzxU
öPõÒÍÄ®. Aa_¨£vÂÀ SøÓ°¸¨¤ß AøÓU PsPõo¨£õÍ›h®
EhÚi¯õPz öu›ÂUPÄ®.
(2) }»® AÀ»x P¸¨¦ ø©°øÚ ©mk÷© GÊxÁuØS®,
AiU÷PõikÁuØS® £¯ß£kzu ÷Ásk®. £h[PÒ ÁøµÁuØS
ö£ß]À £¯ß£kzuÄ®.
(3) ÷uøÁ¯õÚ Ch[PÎÀ £h[PÒ ÁøµP.
Instructions : (1) Check the question paper for fairness of printing. If there is any lack of
fairness, inform the Hall Supervisor immediately.
(2) Use Blue or Black ink to write and underline and pencil to draw
diagrams.
(3) Draw diagrams wherever necessary.

£Sv & I / PART - I
SÔ¨¦ : (i) AøÚzx ÂÚõUPÐUS® Âøh¯ÎUPÄ®. 15x1=15

(ii) öPõkUP¨£mkÒÍ ©õØÖ ÂøhPÎÀ ªPÄ® Hئøh¯ Âøhø¯z
÷uº¢öukzxU SÔ±mkhß Âøh°øÚ²® ÷\ºzx GÊuÄ®.
Note : (i) Answer all the questions.

(ii) Choose the most appropriate answer from the given four alternatives

and write the option code and the corresponding answer.

5962 2

1. ISS Gߣx __________.
(A) C¢v¯ ÂsöÁÎ {ø»¯®
(B) C¢v¯ uµUPmk¨£õk {ÖÁÚ®
(C) £ßÚõmk ÂsöÁÎ {ø»¯®
(D) ÷©Øö\õßÚ GxĪÀø»
ISS stands for __________.
(a) Indian Space Station
(b) Indian Standard System
(c) International Space Station
(d) None of these

2. |õ÷Úõ xPÒPÎß AÍÄ __________.
(A) 100 nm AÀ»x AvP® (B) 10 nm SøÓÁõP
(C) 200 nm (D) 100 nm AÀ»x SøÓÁõP
Size of the Nano particles varies from :
(a) 100 nm or more (b) less than 10 nm
(c) 200 nm (d) 100 nm or less

3. ¤.].G® (PCM) ¯õµõÀ Psk¤iUP¨£mhx ?
(A) â¯õºä ìm÷µõUì (B) µõ£ºm ÷Põa
(C) Aö»Uéõshº ¤Íª[ (D) ¤›mì öéºÛU
Who invented the Phase Contrast Microscope (PCM) ?
(a) George Strokes (b) Robert Koch
(c) Alexander Fleming (d) Frits Zernike

4. £õÀ Gº¼a Psk¤izu \õÀÁº\ß ©¸¢x ________ ]Qaø\US £¯ß£kzu¨£mhx.
(A) {÷©õÛ¯õ (B) öPõ÷Úõ-›¯õ
(C) øh£õ´k (D) ]¤¼ì
Salvarsan was discovered by Paul Ehrlich is used to treat __________.
(a) Pneumonia (b) Gonorrhoea
(c) Typhoid (d) Syphilis

5. ~sq°›PÒ Á͵ HØÓ pH ©v¨¦ __________.
(A) 3.4 (B) 4.0 (C) 9.2 (D) 7.0
The micro-organisms grow best at pH value around __________.
(a) 3.4 (b) 4.0 (c) 9.2 (d) 7.0

3 5962

6. PõØÖÒÍ _Áõ]zu¼À CÖv¯õÚ G»Umµõß Hؤ Gߣx __________.
(A) øímµáß (B) BUêáß (C) Ｏ® (D) ø|mµáß
In an aerobic respiration the terminal electron acceptor is :
(a) Hydrogen (b) Oxygen (c) Helium (d) Nitrogen

7. öuõÈØ\õø» •UQ¯zxÁ® Áõ´¢u ~sq°›PøÍ £u¨£kzu vµÁ
ø|mµáÛÀ __________ öÁ¨£{ø»°À £¯ß£kzu¨£kQÓx.
(A) 72.08C (B) −1968C (C) −1768C (D) 62.88C
__________ temperature is used to preserve industrially important micro-organisms
in liquid nitrogen.
(a) 72.08C (b) −1968C (c) −1768C (d) 62.88C

8. ö©mhõS÷µõ©õiU SÖ©oPøÍ öPõskÒÍ __________ Qµõ® £õ]miÆ
£õ]Àø», ^Ú GÊzxUPøÍ ÷£õßÓ Aø©¨¤À Põn¨£k® £s¦PøÍ
öPõshøÁ.
(A) ÷£]À»ì B¢zµõ]ì
(B) PõºÛ£õUj›¯® i¨vŸ¯õ
(C) QÍõìi›i¯® ö£ºö£›ßöáßì
(D) ø©U÷Põ£õUj›¯® i³£ºS÷Íõêì
A Gram-Positive bacilli possessing metachromatic granules, showing Chinese
letters arrangement are characteristic of :
(a) Bacillus Anthracis
(b) Corynebacterium Diptheriae
(c) Clostridium Perfringens
(d) Mycobacterium Tuberculosis

9. ÃÀì ÷|õ´ ¤ßÁ¸® GÆÁøP £õUj›¯õÁõÀ EshõUP¨£kQÓx ?
(A) ö»¨÷hõìø£µõ Cßhº÷µõPßì
(B) \õÀ÷©õöÚÀ»õ øh¤
(C) ¨›÷¯õ Põ»÷µ
(D) Gèöå›]¯õ ÷Põø»
Weil’s disease is caused by which of the following bacteria ?
(a) Leptospira Interrogans
(b) Salmonella Typhi
(c) Vibrio Cholerae
(d) Escherichia Coli

5962 4

10. ½è÷©Û¯õ E°› ©ÛuÝUS __________ BÀ Phzu¨£kQÓx.
(A) öPõ_ (B) \õsm §a]
(C) öµkÂm §a] (D) ö\m] §a]
Leishmania organism are transmitted to human by :
(a) Mosquitoes (b) Sand Flies
(c) Reduviid Bug (d) Tsetse Flies

11. îì÷hõ¤Íõì÷©õêì __________ GßÓøÇUP¨£k®.
(A) ÷Pßii¯õ]ì (B) \õPõì ÷|õ´
(C) Q›¨÷hõPõU÷Põ]ì (D) hõº¼[ ÷|õ´
Histoplasmosis is also called as __________.
(a) Candidiasis (b) Chagas disease
(c) Cryptococcosis (d) Darling’s disease

12. ø\m÷hõö©Põ÷»õ øÁµìPÒ __________ GßÖ® AøÇUP¨£k®.
(A) |õͪÀ»õa _µ¨¤ øÁµì (B) EªÌ}º _µ¨¤ øÁµì
(C) ¤m³mh› _µ¨¤ øÁµì (D) ö|g\U Pøn¯a _µ¨¤ øÁµì
Cytomegalo Viruses is also called as __________.
(a) Endocrine gland virus (b) Salivary gland virus
(c) Pituitary gland virus (d) Thymus gland virus

13. ÷µ¥ì øÁµì __________ Sk®£zøu \õº¢ux.
(A) öµm÷µõ ›÷h (B) öí¨£õmÚõ ›÷h
(C) ¤Íõ ›÷h (D) ÷µ¨÷hõ ›÷h
Rabies virus belongs to the family __________.
(a) Retero Viridae (b) Hepadna Viridae
(c) Flaviviridae (d) Rhabdoviridae

14. EhÚi ªøP Tº EnºÄ __________ ø¯U SÔUQÓx.
(A) ø\÷éõ÷PõÛ ÂøÚ (B) AÚõø£»õUiU
(C) öµÚõÀmì&¤µõ÷h ÂøÚ (D) i³£ºUS¼ß ÂøÚ
Immediate hypersensitivity refers to __________.
(a) Schizogony Reaction (b) Anaphylactic
(c) Reynolds-Braude Reaction (d) Tuberculin Reaction

5 5962

15. _ØÖ¨¦Ózv¼¸¢x EøÓ¯ØÓ i.Gß.H&øÁ GkzxUöPõÒÐuÀ Gߣx
__________ GÚ¨£k®.
(A) iµõßìL£º÷©åß (B) iµõßìhUåß
(C) ø»]ì (D) Põßã÷Påß
The uptake of naked DNA from the surrounding is known as :
(a) Transformation (b) Transduction
(c) Lysis (d) Conjugation

£Sv & II / PART - II
SÔ¨¦ : GøÁ÷¯Ý® BÖ ÂÚõUPÐUS Âøh¯ÎUPÄ®. ÂÚõ Gs 24 &US
Pmhõ¯©õP Âøh¯ÎUPÄ®. 6x2=12
Note : Answer any six questions. Question No. 24 is Compulsory.
16. DNA Á›ø\¨£kzxu¼ß Cµsk •øÓPøÍ TÖP.
Write two DNA sequencing methods.

17. ¦Ñµ\ßì ~s÷nõUQ°¯¾US £¯ß£kzu¨£k® \õ¯[Pøͨ £mi¯¼kP.
List out the dyes used for fluroscence microscopy.

18. Bßiö\¨iU – Áøµ¯ÖUPÄ®.
Define Antiseptic.

19. JkUP® GßÓõÀ GßÚ ?
What is Reduction ?

20. EnÄ |g\õuÀ – Áøµ¯ÖUPÄ®.
Define Food Poisoning.

21. APõº \õ´Ä GßÓõÀ GßÚ ?
What is Agar Slope ?

22. Põ\÷|õ´US Gvº©¸¢xPÒ H÷uÝ® |õßQøÚ £mi¯¼kP.
List out any four antituberculosis drugs.

5962 6

23. ©xµõø©U÷Põ]ì GßÓõÀ GßÚ ?
What is Maduramycosis ?

24. LD £õiPÒ GßÓõÀ GßÚ ?
What are LD bodies ?

£Sv & III / PART - III
SÔ¨¦ : GøÁ÷¯Ý® BÖ ÂÚõUPÐUS Âøh¯ÎUPÄ®. ÂÚõ Gs 33 &US
Pmhõ¯©õP Âøh¯ÎUPÄ®. 6x3=18
Note : Answer any six questions. Question No. 33 is Compulsory.
25. TEM&°ß H÷uÝ® ‰ßÖ £s¦PøÍ £ØÔ GÊxP.
Write three properties of TEM.

26. 'E' & ÷\õuøÚ GßÓõÀ GßÚ ?
What is meant by E-test ?

27. ø»÷¯õ¤ø»÷\åß GßÓõÀ GßÚ ?
What is meant by Lyophilisation ?

28. EnÂÀ ~sq°›PÎß Buõµ[PÒ H÷uÝ® BÔøÚ £mi¯¼kP.
List out any six sources of micro-organisms in food.

29. Gsh«£õ îì÷hõ¼iUPõÂß m÷µõ÷£õ÷\õ°møh £h® Áøµ¢x £õP[PøÍU
SÔUPÄ®.
Draw the diagram of a Trophozoite of Entamoeba histolytica and label the parts.

30. öẮ SÇõ´ ÷\õuøÚ – Áøµ¯ÖUPÄ®.
Define Germ Tube Test.

31. âPõ Põ´a\À GßÓõÀ GßÚ ?
What is Zika Fever ?

7 5962

32. öÁìhß ¤Íõm öuõÈÀ~m£zvß £¯ßPÒ ¯õøÁ ?
Write the applications of Western Blot Techniques.

33. ÷|õ÷\õ÷Põª¯À ÷|õ´zöuõØÖ £ØÔ GÊxP.
Write about Nosocomial Infection.

£Sv & IV / PART - IV
SÔ¨¦ : AøÚzx ÂÚõUPÐUS® Âøh¯ÎUPÄ®. 5x5=25
Note : Answer all the questions.
34. (A) DNA Á›ø\¨£kzxuÀ •øÓPÒ £ØÔ ÂÁ›UPÄ®.
AÀ»x
(B) £õUj›]hÀ ©ØÖ® £õUj›÷¯õìhõiUQß ÷ÁÖ£õkPøÍ GÊxP.
(a) Write in detail about DNA sequencing methods.
OR
(b) Write the difference between Bactericidal and Bacteriostatic.

35. (A) ¦÷Íõµ\ßì ~s÷nõUQ°ß ö\¯À C¯[Pø©¨ø£ £hzxhß ÂÁ›UPÄ®.
AÀ»x
(B) MBRT &ö©zv½ß }» \õ¯ JkUP ÷\õuøÚø¯ ÂÁ›UPÄ®.
(a) Explain the working mechanism of Fluorescence Microscope.
OR
(b) Write in detail about Methylene Blue dye Reduction Test (MBRT).

36. (A) ö£Û]¼ß u¯õ›¨¦ •øÓPøÍ ÂÁ›UPÄ®.
AÀ»x
(B) Gsh«£õ îì÷hõ¼iUPõÂß ÁõÌUøP _ÇØ]ø¯ ÂÁ›UPÄ®.
(a) Explain the process of penicillin production.
OR
(b) Write in detail about the life cycle of E. Histolytica.

5962 8

37. (A) uõøh & G¾®¦ ¤i¨¦ ÷|õ°ß ÷|õ´z÷uõØÓ® £ØÔ ÂÁ›UPÄ®.
AÀ»x
(B) Gø»\õ GßÓõÀ GßÚ ? Auß uzxÁzøu ÂÁ›UPÄ®.
(a) Describe the Pathogenesis of Lock-Jaw disease.
OR
(b) What is meant by ELISA ? Explain the principles of ELISA.

38. (A) öí¨£øhiì A øÁµì £ØÔ ÂÁ›UPÄ®.
AÀ»x
(B) PCR ÷\õuøÚø¯¨ £ØÔ ÂÁ›UPÄ®.
(a) Explain in detail about Hepatitis A virus.
OR
(b) Explain PCR-Polymerase Chain Reaction.

-o0o-

No. of Printed Pages : 8
5963
!5963BioChemistry! £vÄ Gs
Register Number

PART - III
E°º ÷Áv°¯À / BIO-CHEMISTRY
(uªÌ ©ØÖ® B[Q» ÁÈ / Tamil & English Version)

Põ» AÍÄ : 3.00 ©o ÷|µ® ] [ ö©õzu ©v¨ö£sPÒ : 70

Time Allowed : 3.00 Hours ] [ Maximum Marks : 70

AÔÄøµPÒ : (1) AøÚzx ÂÚõUPЮ \›¯õP £vÁõQ EÒÍuõ GߣuøÚ \›£õºzxU
öPõÒÍÄ®. Aa_¨£vÂÀ SøÓ°¸¨¤ß AøÓU PsPõo¨£õÍ›h®
EhÚi¯õPz öu›ÂUPÄ®.
(2) }»® AÀ»x P¸¨¦ ø©°øÚ ©mk÷© GÊxÁuØS®
AiU÷PõikÁuØS® £¯ß£kzu ÷Ásk®. £h[PÒ ÁøµÁuØS
ö£ß]À £¯ß£kzu ÷Ásk®.
(3) ÷uøÁ¯õÚ ChzvÀ Áøµ£h® ©ØÖ® \©ß£õkPøÍz u¸P.
Instructions : (1) Check the question paper for fairness of printing. If there is any lack of
fairness, inform the Hall Supervisor immediately.
(2) Use Blue or Black ink to write and underline and pencil to draw
diagrams.
(3) Draw diagrams and write equations wherever necessary.

£Sv & I / PART - I

SÔ¨¦ : (i) AøÚzx ÂÚõUPÐUS® Âøh¯ÎUPÄ®. 15x1=15

(ii) öPõkUP¨£mkÒÍ ©õØÖ ÂøhPÎÀ ªPÄ® Hئøh¯ Âøhø¯z
÷uº¢öukzxU SÔ±mkhß Âøh°øÚ²® ÷\ºzx GÊuÄ®.

Note : (i) Answer all the questions.
(ii) Choose the most appropriate answer from the given four alternatives
and write the option code and the corresponding answer.