Tamil Nadu 12th Std Model Question Paper Bio-Chemistry

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No. of Printed Pages : 8
3313 (NS)
!3313NSBIOCHEMISTRY! £vÄ Gs
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PART - III
E°º ÷Áv°¯À / BIO-CHEMISTRY
(uªÌ ©ØÖ® B[Q» ÁÈ / Tamil & English Version)

Põ» AÍÄ : 3.00 ©o ÷|µ® ] [ ö©õzu ©v¨ö£sPÒ : 70

Time Allowed : 3.00 Hours ] [ Maximum Marks : 70

AÔÄøµPÒ : (1) AøÚzx ÂÚõUPЮ \›¯õP £vÁõQ EÒÍuõ GߣuøÚ
\›£õºzxU öPõÒÍÄ®. Aa_¨£vÂÀ SøÓ°¸¨¤ß AøÓU
PsPõo¨£õÍ›h® EhÚi¯õPz öu›ÂUPÄ®.
(2) }»® AÀ»x P¸¨¦ ø©°øÚ ©mk÷© GÊxÁuØS®
AiU÷PõikÁuØS® £¯ß£kzu ÷Ásk®. £h[PÒ ÁøµÁuØS
ö£ß]À £¯ß£kzu ÷Ásk®.
(3) ÷uøÁ¯õÚ ChzvÀ Áøµ£h® ©ØÖ® \©ß£õkPøÍz u¸P.
Instructions : (1) Check the question paper for fairness of printing. If there is any lack of
fairness, inform the Hall Supervisor immediately.
(2) Use Blue or Black ink to write and underline and pencil to draw diagrams.
(3) Draw diagrams and write equations wherever necessary.

£Sv & I / PART - I
SÔ¨¦ : (i) AøÚzx ÂÚõUPÐUS® Âøh¯ÎUPÄ®. 15x1=15
(ii) öPõkUP¨£mkÒÍ ©õØÖ ÂøhPÎÀ ªPÄ® Hئøh¯
Âøhø¯z ÷uº¢öukzxU SÔ±mkhß Âøh°øÚ²® ÷\ºzx
GÊuÄ®.
Note : (i) Answer all the questions.
(ii) Choose the most appropriate answer from the given four alternatives and
write the option code and the corresponding answer.

[ v¸¨¦P / Turn over

3313 (NS) 2

1. __________ ¦µ- u [- P - Î - Ú õÀ ÷\õ- i - ¯ ® ©Ø- Ö ® ö£õm- h õ- ] - ¯ ®
Phz-u¨£-kQß-Ó-Ú.
(A) ö|õ-v (B) H¢-v
(C) Phz-x-Á-È (D) Enº-÷ÁØ-¤
Sodium and Potassium are transported by a __________ protein.
(a) enzyme (b) carrier
(c) channel (d) receptor

2. ¤z-u¨ø£ PØ-PÒ __________ BÀ BU-P¨-£m-kÒÍ-Ú.
(A) QøÍ-^ß (B) ³›U Aª-»®
(C) öPõ-»ì-i-µõÀ (D) PõÀ-]-¯® BU-\-÷»m
Gall stones are made up of __________.
(a) Glycine (b) Uric acid
(c) Cholesterol (d) Calcium oxalate

3. HMP Cønz-u-h ÁÈ-°À E¸-Áõ-S® JkU-Pz-v-Óß :
(A) FADH2 (B) NADH (C) NADPH (D) FAD
The important reducing power produced in HMP shunt pathway is :
(a) FADH2 (b) NADH (c) NADPH (d) FAD

4. Põº-£-ø©À £õì-÷£m ]¢-u-÷hì-- - I CvÀ Põ-n¨-£-k-Q-Óx :
(A) Em-P-¸
(B) ø©m-÷hõ-Põs-i-›-¯õ
(C) ø\÷hõ-\õÀ
(D) ø©m-÷hõ-Põs-i-›-¯õ-ÂÀ J¸ £S-v-¯ÍÄ ©Ø-Ö® ø\m-÷hõ-\õ-¼À J¸
£S-v-²® Põ-n¨-£-k-Q-Ó-x
Carbamoyl Phosphate Synthetase - I is present in the :
(a) Nucleus
(b) Mitochondria
(c) Cytosol
(d) Partly in mitochondria and partly in the cytosol

3 3313 (NS)

5. ì¤ß-÷Põ-¼¨-¤-k-P-ÎÀ Põ-n¨-£-k® Aª-÷Úõ BÀ-P-íõÀ Gx ?
(A) C÷Úõ-]-hõÀ (B) ^øµß
(C) -÷Põ-ø»ß (D) ì¤ß-÷Põ-ø\ß
__________ is the amino alcohol present in Sphingolipids.
(a) Inositol (b) Serine
(c) Choline (d) Sphingosine

6. DNA &Â-¼-¸¢x ø\m-÷hõ-¤Íõ-\z-vØS ©µ-¦z uP-ÁÀ-PøÍ _©¢x ö\À-¾® RNA
Gx ?
(A) tRNA ©Ø-Ö® rRNA (B) rRNA
(C) mRNA (D) tRNA
__________ type of RNA carries the genetic information from the DNA to the
Cytoplasm.
(a) tRNA and rRNA (b) rRNA
(c) mRNA (d) tRNA

7. ©µ-¦z-u-P-ÁÀ ö©õ-È-ö£-¯ºz-u-¼À Dk-£-k® ø\m-÷hõ-¤Íõ\ ö\À EÒ-Ð-Ö¨-¦
__________.
(A) øu»-Põ´-k (B) ø»÷\õ-÷\õ®
(C) ›÷£õ-÷\õ® (D) £_[-P-o-P®
The cytoplasmic cellular organelle involved in translation process is __________.
(a) Thylakoids (b) Lysosome
(c) Ribosome (d) Chloroplast

8. SÐU-÷Põì&6&£õì£-÷hì SøÓ-£õk, E¸-ÁõU-S-Áx :
(A) ï÷©õ-¥-¼-¯õ (B) Põ-»U-÷hõ-^-ª-¯õ
(C) AÀ-¤-Û-\® (D) Áõß&-Q-ŸUì ÷|õ´
Glucose-6-phosphatase deficiency causes :
(a) haemophilia (b) galactosemia
(c) albinism (d) Von-gierke’s diseases

[ v¸¨¦P / Turn over

3313 (NS) 4

9. Ps-P-ÎÀ HØ-£-k® {Ó-ªU SøÓ-£õk ¤ß-Á-¸-©õÖ AøÇU-P¨-£-k-Q-Óx :
(A) ï÷©õ-¤-¼-¯õ (haemophilia)
(B) ÂÈ-°-ÝÒ AÀ-¤-Û-\® (ocular albinism)
(C) ÂÈ-`Ì AÀ-¤-Û-\® (oculo - cutaneous albinism)
(D) AÀ-Põ¨-÷hõ-Þ-›-¯õ (alkaptonuria)
The decreased pigmentation in eyes are called as __________.
(a) haemophilia
(b) ocular albinism
(c) oculo - cutaneous albinism
(d) alkaptonuria

10. BU-ê-á-÷ÚØÓ £õì-£õ-›-÷»Ø-Óz-vß Cønuk¨-£õß :
(A) ÷µõm-÷Úõß (B) DNP
(C) DTT (D) Aø\-k
A uncoupler of oxidative phosphorylation is __________.
(a) Rotenone (b) DNP
(c) DTT (d) Azide

11. NADH &¼-¸¢x 2 Gö»Um-µõß-PÒ •Ê-ø©-¯õP BU-ê-á-ÝUS Phz-x® ETC
ö\¯À- • - ø Ó- ° ß Áõ- ° - » õP Gz- u øÚ ‰»U- T - Ö - P Ò ATP E¸- Á õU- P ¨
-£-k-Qß-ÓÚ ?
(A) 1 ATP (B) 4 ATP (C) 3 ATP (D) 2 ATP
How many ATP is generated when there is a complete transfer of 2 electrons from
NADH through the entire ETC to oxygen ?
(a) 1 ATP (b) 4 ATP (c) 3 ATP (d) 2 ATP

12. M-M \©ß-£õm-iß uø»-RÌ Ái-Ázøu B÷»õ-]z-u-Áº :
(A) ø©÷P-¼ì ö©ß-hß (B) ø»ßÃÁº & £ºU
(C) ¤è-åº (D) ÷Põè-÷»sm
The reciprocal form of M-M equation was considered by :
(a) Michaélis Menten (b) Lineweaver - Burk
(c) Fischer (d) Koshland

5 3313 (NS)

13. Bß-i-öáß-PÒ ÂøÚ-¦-›-Á-uõÀ B - ö\ÀPÎ-¼-¸¢x E¸-Áõ-S®- ¦-µ-u® :
(A) wµ {ø» ¦µ-u® (B) Bß-i-£õ-i
(C) Cs-hº-ö£-µõß (D) {µ¨-¦U Põ-µ-o
Name the protein produced in response to and counteracting a specific antigen from
B - Cells.
(a) acute phase protein (b) antibody
(c) interferon (d) complement

14. RÌU-Ps-h-ÁØ-ÔÀ Gx `¨-£º Bß-i-öáß ?
(A) ÷í¨-÷hß (B) Bm-÷hõ-áß
(C) TSST - 1 (D) hõU-éõ´-k
Which one of the following is a superantigen ?
(a) Hapten (b) Autogen
(c) TSST - 1 (d) Toxoid

15. IgM Bß-i-£õ-i-°À EÒÍ Bß-i-öáß Cøn-²® £S-v-P-Îß Gs-oUøP :
(A) 10 (B) 7 (C) 8 (D) 9
Number of antigen binding sites in IgM antibody are :
(a) 10 (b) 7 (c) 8 (d) 9

£Sv & II / PART - II
SÔ¨¦ : H÷uÝ® 6 ÂÚõUPÐUS Âøh¯ÎUPÄ®. ÂÚõ Gs 24 &US
Pmhõ¯® Âøh¯ÎUPÄ®. 6x2=12
Note : Answer any 6 questions. Question No. 24 is compulsory.

16. uø\ ö|QÌÄ (tonicity) £ØÔ-¯ Eß P¸zøu GÊ-x-P.
Give your idea on tonicity.

17. öuÂm-i¯ {ø» & Áøµ-¯-ÖU-P-Ä®.
Define the term Satiety.

18. EªÌ }›ß Cø¯¦ ©Ø-Ö® ö\¯À-£õ-k-PÒ Cµs-iøÚ u¸-P.
Give the composition and any two functions of Saliva.

[ v¸¨¦P / Turn over

3313 (NS) 6

19. GTT £ØÔ ]Ö SÔ¨¦ Áøµ-P.
Write a short note on GTT.

20. øu÷µõ-]-Û-¼-¸¢x E¸-Áõ-S® •U-Q¯ Âøͨ- ö£õ-¸m-PÒ ¯õøÁ ?
What are the specialized products formed from tyrosine ?

21. øÁm-h-ªß D &°ß E°-›-¯À •U-Q-¯z-x-Ázøu GÊ-x-P.
Write the biological importance of Vitamin D.

22. DNA Cµm-i¨-£-øh-u-¼ß ‰ßÖ Âu-©õÚ ©õ-v-›-PøÍ SÔ¨-¤-k-P.
Mention the three models of DNA replication.

23. ÷Á›-÷¯õ-ö»-åß & Áøµ-¯-ÖU-P-Ä®.
Define variolation.

24. ATP &ø¯ E¸-ÁõU-S-Á-vÀ ATP ]¢÷uì ö|õ-v-°ß £[S GßÚ ?
What is the role of ATP Synthase in the formation of ATP ?

£Sv & III / PART - III

SÔ¨¦ : H÷uÝ® 6 ÂÚõUPÐUS Âøh¯ÎUPÄ®. ÂÚõ Gs 33 &US
Pmhõ¯©õP Âøh¯ÎUPÄ®. 6x3=18
Note : Answer any 6 questions. Question No. 33 is compulsory.

25. \Æ-Ä-P-ÎÀ Põ-n¨-£-k® ‰ßÖ ÁøP-¯õÚ QøÍU-÷Põ-¼¨-¤-k-PÒ ¯õøÁ ?
What are the three types of glycolipids in the membrane ?

26. Aª- ÷ Úõ Aª- » [- P Ò EÔg- \ ¨- £ - k - u ø» £õ- - v U- S ® ‰ßÖ Põ- µ - o - P øÍ
GÊ-x-P.
Write any three factors that affect absorption of amino acids.

27. QøÍU-÷Põ-ã-÷Úõ-ø»-êì Gß-ÓõÀ GßÚ ?
What is glycogenolysis ?

7 3313 (NS)

28. A®-÷©õ-Û-¯õ |a-\õ-uÀ Gß-ÓõÀ GßÚ ? Auß AÔ-S-Ô-PøÍ u¸-P.
What is ammonia intoxication ? Give its symptoms.

29. öPõ-»ì-i-µõ-¼ß £s-¦-PÒ ‰ß-ÔøÚ GÊ-x-P.
Write any three properties of Cholesterol.

30. E¯º BØ-ÓÀ £õì-÷£m ¤øn¨-¦-PÒ £ØÔ GÊ-x-P.
Give a note on high energy phosphate bonds.

31. §m-ka \õ ©õ-v-›-°ß £i Q꼀 ø©¯z-vß ußø© ¯õx ?
What is the nature of active site according to lock and key theory ?

32. ÷|õ-°-¯À & Áøµ-¯-ÖU-P-Ä®.
Define Epidemiology.

33. øÁhõÀ ÷\õ-uøÚ (Widal test) £ØÔ SÔ¨¦ Áøµ-P.
Write a note on Widal Test.

£Sv & IV / PART - IV
SÔ¨¦ : AøÚzx ÂÚõUPÐUS® Âøh¯ÎUPÄ®. ÷uøÁ-¯õÚ Ch[-P-ÎÀ
£h® Áøµ-P. 5x5=25
Note : Answer all the questions. Draw diagrams wherever necessary.

34. (A) \Æ-Åk £µ-Á-¼ß E°-›-¯À •U-Q-¯z-x-Ázøu u¸-P.
AÀ»x
(B) Põº- ÷ £õ- ø ím- ÷ µm- P Ò EÔg- \ ¨- £ - k - u - ø » £õ- v U- S ® Põ- µ - o - P øÍ
£m-i-¯-¼-k-P.
(a) Give the biological significance of Osmosis.
OR
(b) List down the factors that affect the absorption of carbohydrates.

[ v¸¨¦P / Turn over

3313 (NS) 8

35. (A) QøÍU-Põ-ø»]ì ö\¯À-•-øÓ-°ß öuõ-hº ÂøÚ-PøÍ GÊ-x-P.
AÀ»x
(B) ÷Pm-h-Põ-»-«ß-PÒ E¸-Áõ-uÀ ÂøÚ-÷¯õk öuõ-hº-¦-øh¯ £i-{-ø»-PøÍ
ÂÍU-S-P.
(a) What are the reaction sequences of glycolysis ?
OR
(b) Enumerate the steps involved in the formation of catecholamines.

36. (A) |©x Eh-¼À öPõ-ʨ¦ Aª-»[-PÒ GÆ-ÁõÖ öuõSU-P¨-£-k-Q-Óx ?
AÀ»x
(B) DNA Cµm-i¨-£-øh-u-¼À {P-Ê® {PÌ-Ä-PøÍ £hz-x-hß ÂÁ-›U-P-Ä®.
(a) How are fatty acids synthesized in our body ?
OR
(b) Explain the events involved in DNA replication with a neat sketch.

37. (A) AÀ-Põ¨-÷hõ-Þ-›-¯õ £ØÔ SÔ¨¦ Áøµ-P.
AÀ»x
(B) ÷£õm-iz uß-ø©-²ÒÍ ©Ø-Ö® ÷£õm-iz uß-ø©-¯ØÓ ukz-uÀ J¨-¤-k-P.
(a) Give an account on alkaptonuria.
OR
(b) Compare competitive and non-competitive inhibition.

38. (A) EhØ-Põ¨¦ ‰»z-vß Aø©¨ø£ £hz-x-hß ÂÁ-›U-P-Ä®.
AÀ»x
(B) ÷Áva \Æ-Åk £µ-ÁÀ öPõÒ-øPø¯ ÂÁ-›U-P-Ä®.
(a) Describe the structure of antibody with a neat diagram.
OR
(b) Describe Chemiosmotic theory.

-oOo-