TN 12th Question Paper 2024 Bio-Chemistry

TN PUBLIC EXAM

QUESTION
PAPER
2024

No. of Printed Pages : 8
7463
!7463BioChemistry! £vÄ Gs
Register Number

PART - III
E°º ÷Áv°¯À / BIO-CHEMISTRY
(uªÌ ©ØÖ® B[Q» ÁÈ / Tamil & English Version)

Põ» AÍÄ : 3.00 ©o ÷|µ® ] [ ö©õzu ©v¨ö£sPÒ : 70

Time Allowed : 3.00 Hours ] [ Maximum Marks : 70

AÔÄøµPÒ : (1) AøÚzx ÂÚõUPЮ \›¯õP £vÁõQ EÒÍuõ GߣuøÚ \›£õºzxU
öPõÒÍÄ®. Aa_¨£vÂÀ SøÓ°¸¨¤ß AøÓU PsPõo¨£õÍ›h®
EhÚi¯õPz öu›ÂUPÄ®.
(2) }»® AÀ»x P¸¨¦ ø©°øÚ ©mk÷© GÊxÁuØS®
AiU÷PõikÁuØS® £¯ß£kzu ÷Ásk®. £h[PÒ ÁøµÁuØS
ö£ß]À £¯ß£kzu ÷Ásk®.
(3) ÷uøÁ¯õÚ ChzvÀ Áøµ£h® ©ØÖ® \©ß£õkPøÍz u¸P.
Instructions : (1) Check the question paper for fairness of printing. If there is any lack of fairness,
inform the Hall Supervisor immediately.
(2) Use Blue or Black ink to write and underline and pencil to draw diagrams.
(3) Draw diagrams and write equations wherever necessary.

£Sv & I / PART - I

SÔ¨¦ : (i) AøÚzx ÂÚõUPÐUS® Âøh¯ÎUPÄ®. 15x1=15

(ii) öPõkUP¨£mkÒÍ |õßS ©õØÖ ÂøhPÎÀ ªPÄ® Hئøh¯
Âøhø¯z ÷uº¢öukzx SÔ±mkhß Âøh°øÚ²® ÷\ºzx
GÊuÄ®.

Note : (i) Answer all the questions.
(ii) Choose the most appropriate answer from the given four alternatives and write
the option code and the corresponding answer.

[ v¸¨¦P / Turn over

7463 2

1. Eh-¼-¯À AÀ-»x I÷\õ-hõ-ÛU E¨-¦-}ºU P»-øÁ Gß-£x __________.
(A) 0.9% NaCl (B) 0.3% NaCl (C) 1.5% NaCl (D) 0.6% NaCl
The physiological or isotonic saline is __________.
(a) 0.9% NaCl (b) 0.3% NaCl (c) 1.5% NaCl (d) 0.6% NaCl

2. ]Ö-Sh- ¼
- ß EÒ-£µ- ¨-¤À Sh-¾Ô
- g-]P
- Ð
- US Cøh-÷¯ Aø©¢-xÒÍ S-ÇÀ _µ¨-¤P
- Ò
__________ .
(A) Am-Ÿ-ÚÀ _µ¨-¤ (B) ½£º-Sß _µ¨-¤-PÒ
(C) øuµõ´k _-µ¨-¤ (D) ¦¸ß-Úº _µ¨-¤-PÒ
The tubular glands that lie between the villi of the inner surface of the small intestine is
__________.
(a) Adrenal gland (b) Lieberkuhn glands
(c) Thyroid gland (d) Brunner’s glands

3. ES AønÄ E¸-Áõ-uÀ J¸ __________.
(A) BØ-ÓÀ EÔg-_® ÂøÚ (B) «Ò ÂøÚ
(C) •Ê-ø©-¯õÚ ÂøÚ (D) «Íõ ÂøÚ
ES complex formation is a/an __________.
(a) energy consuming reaction (b) reversible reaction
(c) complete reaction (d) irreversible reaction

4. G¤-ö|¨-›ß, Q›-¯õm-iß ©Ø-Ö® u¯-ªß BQ-¯Á - Ø-Ôß öuõ-Sz-u¼
- À ö©z-vÀ öuõ-Sv
ÁÇ[-Q-¯õP ö\¯À-£-k-Áx __________.
(A) öhm-µõ-øím-÷µõ-÷£õ-÷»m (B) ö©z-÷uõm-µU-÷ém
(C) £÷¯õm-iß (D) S - Ai-÷Úõ-]À ö©z-v-÷¯õ-øÚß
__________ acts as methyl group donor for the synthesis of epinephrine, creatine and thymine.
(a) Tetrahydrofolate (b) Methotrexate
(c) Biotin (d) S - Adenosyl methionine

5. |g-_U-öPõ-iø¯ PhU-S® Bß-i-£õi __________.
(A) IgM (B) IgG (C) IgE (D) IgA
The antibody which crosses placenta is __________.
(a) IgM (b) IgG (c) IgE (d) IgA

3 7463

6. Aø\-÷£õ-k® E°-›-Ú[-P-ÎÀ SÐU-÷Põ-]ß •ußø© ‰»® __________.
(A) -]m-÷µm (B) Q-Î-\-µõÀ
(C) ¦µ¨-¤-÷¯õ-÷Úm (D) »õU-÷hm
The major source of glucose in ruminants is __________.
(a) Citrate (b) Glycerol
(c) Propionate (d) Lactate

7. J¸ SÇ¢- ø u- ° ß ]Ö- } - µ õ- Ú x PõØ- Ô À £k®- ÷ £õx P¸- ø © {Ó- © õP ©õ- Ö - Q - Ó x.
Cv-¼-¸¢x } ³Qz-u-Ô-²® \õz-v-¯-©õÚ SøÓ-£õk Gx ?
(A) Põ-»U-÷hõ-^-ª-¯õ (B) ÷h&\õUì ÷|õ´
(C) AÀ-Põ¨-÷hõ-Þ-›-¯õ (D) QøÍU-÷Põ-áß ÷\P-µ-©õ-S® ÷|õ´
A child’s urine on exposure to air became dark coloured. What is your probable diagnosis ?
(a) Galactosemia (b) Tay-Sachs disease
(c) Alkaptonuria (d) Glycogen storage disease

8. {Özu ÷Põ-hõß Gß-£x __________.
(A) UUA (B) UAG (C) UAC (D) AUG
The stop codon is __________.
(a) UUA (b) UAG (c) UAC (d) AUG

9. ¤ß-Á-¸-Á-Ú-ÁØ-ÔÀ Gx öPõ-»ì-i-µõ-¼ß ö£Ö-v-PÒ AÀ» ?
(A) øÁm-h-ªß A (B) ¤zu E¨-¦-PÒ
(C) øÁm-h-ªß D (D) ìj-µõ´k íõº-÷©õß-PÒ
Which of the following is not a derivative of cholesterol ?
(a) Vitamin A (b) Bile salts
(c) Vitamin D (d) Steroid hormones

10. AÇØ-]-°ß÷£õx E¸-Áõ-S® Põº-i-ÚÀ AÔ-S-Ô-¯õÚ ""÷hõ-»º'' (dolor) Gß-£x
__________ .
(A) -öÁ¨-£® (B) ÃU-P®
(C) Á¼ (D) ]Á¨-£õP ©õ-Ö-uÀ
The cardinal sign of inflammatory response “dolor” refers to __________.
(a) Heat (b) Swelling
(c) Pain (d) Redness

[ v¸¨¦P / Turn over

7463 4

11. En-Ä Esn \ªUøb uµ Põ-µ-n-©õÚ íõº-÷©õß __________.
(A) Gs-i-÷µõ-÷Pìm-÷µõß (B) öP›-¼ß
(C) ÷©õ-i-¼ß (D) PYY
__________ is a hormone responsible for signaling to eat.
(a) Enterogastrone (b) Ghrelin
(c) Motilin (d) PYY

12. NADH iøím-µ-á-÷Ú-êß Cønz öuõ-Sv __________.
(A) FAD (B) FMN (C) NADPH (D) NADH
The prosthetic group of NADH dehydrogenase is __________.
(a) FAD (b) FMN (c) NADPH (d) NADH

13. SÐU-÷Põì 6-£õì-£-÷hì SøÓ-£õk E¸-ÁõU-S-Áx __________.
(A) Áõß&-Q-ŸUì ÷|õ´ (B) Põ-»U-÷hõ-^-ª-¯õ
(C) ï÷©õ-¥-¼-¯õ (D) AÀ-¤-Û-\®
Glucose 6-phosphatase deficiency causes __________.
(a) Von-Gierke disease (b) Galactosemia
(c) Hemophilia (d) Albinism

14. ys-h¨-£mh ö£õ-¸¢-x-uÀ ©õ-v-›ø¯ E¸-ÁõU-Q-¯-Áº :
(A) ÷Põè-÷»sm (B) iU-\õß
(C) ø©U-P-¼ì ö©ß-hß (D) ¤è-åº
Induced Fit Model was proposed by :
(a) Koshland (b) Dixon
(c) Michaelis Menten (d) Fischer

15. Es-nõ {ø»-°À C¯À-£õÚ SÐU-÷Põ-êß AÍÄ __________.
(A) 200 mg/dl Âh Av-P® (B) 100 - 150 mg/dl
(C) 100 mg/dl ÂhU SøÓ-Ä (D) 150 - 200 mg/dl
Normal glucose level during fasting is __________.
(a) Greater than 200 mg/dl (b) 100 - 150 mg/dl
(c) Less than 100 mg/dl (d) 150 - 200 mg/dl

5 7463

£S-v & II / PART - II
SÔ¨¦ : H÷u- Ý ® BÖ ÂÚõU- P - Ð US Âøh- ¯ - Î U- P - Ä ®. ÂÚõ Gs 24 &US
Pm-hõ-¯-©õP Âøh-¯-ÎU-P-Ä®. 6x2=12

Note : Answer any six questions. Question No. 24 is compulsory.

16. §mk \õ ©õ-v-›-°ß-£i, Q꼀 ø©¯z-vß ußø© ¯õx ?
What is the nature of active site according to Lock and Key theory ?

17. Cøh¨-ö£õ-vÄ Aø©¨¦ ©õ-v-›-°ß SøÓ-£õ-k-PÒ ¯õøÁ ?
What are the drawbacks of sandwich model ?

18. ÷Á-›-÷¯õ-÷»-åß (Variolation) – Áøµ-¯-ÖU-P-Ä®.
Define Variolation.

19. øu÷µõ-]-Û-¼-¸¢x E¸-Áõ-S® •U-Q¯ ÂøÍö£õ-¸m-PøÍU SÔ¨-¤-k-P.
Mention the specialized products formed from tyrosine.

20. £i-ö¯-kz-uÀ Gß-ÓõÀ GßÚ ?
What is meant by transcription ?

21. Põº- ÷ £õ- ø ím- ÷ µm- k - P øÍ ö\›¨- £ - v À, EªÌ- } º Aø©- ÷ »øé Âh Pøn- ¯
Aø©-÷»ì ÷©®-£m-hx. Hß ?
Why is pancreatic amylase superior to salivary amylase in digesting carbohydrates ?

22. Põ-»U-÷hõ-^-ª-¯õ-Âß AÔ-S-Ô-PÒ ¯õøÁ ?
What are the symptoms of galactosemia ?

23. ø£¸-÷Ám GÆ-ÁõÖ »õU-÷hm-hõP ©õØ-Ó¨-£-k-Q-Óx ?
How pyruvate is converted to lactate ?

24. ø»÷\õ-ö»-]z-v-Ûß ÂøÍ-Ä-PÒ ¯õøÁ ?
What are the effects of lysolecithin ?

[ v¸¨¦P / Turn over

7463 6

£S-v & III / PART - III
SÔ¨¦ : H- ÷ u- Ý ® BÖ ÂÚõU- P - Ð US Âøh- ¯ - Î U- P - Ä ®. ÂÚõ Gs 33 &US
Pm-hõ-¯-©õP Âøh-¯-ÎU-P-Ä®. 6x3=18

Note : Answer any six questions. Question No. 33 is compulsory.

25. £õ-S-{-ø»z uß-ø©-°ß E°-›-¯À •U-Q-¯z-x-Áz-øuz u¸-P.
Give the biological significance of viscosity.

26. RNA &ÂÀ £i-ö¯-kz-u-¾U-S¨ ¤ß {P-Ê® ©õØ-Ó[-PøÍU SÔ¨-¤-k-P.
Mention the post transcriptional modifications of RNA.

27. mµõßì Aª-÷ÚØ-Óz-vß £s-¦-PøÍ £m-i-¯-¼-k-P.
List down the features of transamination.

28. G»Um-µõß Phz-xa \[-Q-¼-°ß uk¨-£õß-PÒ £ØÔ SÔ¨¦ Áøµ-P.
Write a note on the inhibitors of electron transport chain.

29. QøÍU-Põ-¼-]ì {PÌ-Âß ‰ßÖ •U-Q¯ «Íõ ÂøÚ-PøÍ GÊ-x-P.
Write the three important irreversible reactions in glycolysis.

30. ÷|õ´ Gvº¨¦ {øÚ-ÁõØ-Ó-¼ß •U-Q-¯z-x-Á® ¯õx ?
What is the significance of immunologic memory ?

31. Bz-v-÷µõì-Q-Î-÷µõ-]ì £ØÔ ]Ö SÔ¨¦ Áøµ-P.
Give a short note on atherosclerosis.

32. Tm-k-~s öPõ-ʨ-¦¨ ö£õ-¸Ò GÆ-ÁõÖ E-¸-Áõ-Q-Óx ?
How are mixed micelle formed ?

33. «Ò ukz-uÀ Gß-ÓõÀ GßÚ ? AÁØ-Ôß ÁøP-PøÍ GÊ-x-P.
What is reversible inhibition ? Write their types.

7 7463

£S-v & IV / PART - IV
SÔ¨¦ : AøÚz-x ÂÚõU-P-ÐU-S® Âøh-¯-ÎU-P-Ä®. ÷uøÁ-¯õÚ Ch[-P-ÎÀ £h®
Áøµ-P. 5x5=25

Note : Answer all questions. Draw the diagrams wherever necessary.

34. (A) \ÆÄ Phz-uÀ £ØÔ Â›-ÁõÚ ÂÍU-P® u¸-P.
AÀ-»-x
(B) ø»ß-ÃÁº £ºU Áøµ-£-h® GÆ-ÁõÖ ö£Ó¨-£-k-Q-Óx ?
(a) Give a detailed note on membrane transport.

OR

(b) How is Lineweaver Burk plot arrived ?

35. (A) ö\À-Â-Ê[-S-u-¼À {P-Ê® £i-PøÍ ÂÍU-S-P.
AÀ-»-x
(B) ÷h&\õUì ÷|õ-°ß Põ-µ-n® ©Ø-Ö® AÔ-S-Ô-PøÍ ÂÁ-›U-P-Ä®.
(a) Explain the steps involved in phagocytosis.

OR

(b) Describe the causes and symptoms of Tay-Sachs disease.

36. (A) ÷Pm-h-Põ»«ß-PÒ E¸-ÁõU-Pz-vÀ EÒÍ £i-{-ø»-PøÍ ÂÍU-S-P.
AÀ-»-x
(B) ¦÷µõ-÷P-›-÷¯õm-k-PÒ ©Ø-Ö® ³÷P-›-÷¯õm-k-P-ÎÀ {P-Ê® DNA Cµm-i¨-&
£-øh-u-¼ß ö\¯À-•-øÓ-PøÍ ÷ÁÖ-£-kz-x-P.
(a) Explain the steps involved in the formation of catecholamines.

OR

(b) Differentiate between the process of DNA replication in prokaryotes and eukaryotes.

[ v¸¨¦P / Turn over

7463 8

37. (A) PÀ-½-µ-¼ß ö\¯À-£õ-k-Pøͨ £m-i-¯-¼-k-P.
AÀ-»-x
(B) öPõ-»ì-i-µõÀ E°º-öuõ-Sz-u-¼À EÒÍ £À-÷ÁÖ £i-{-ø»-PøÍ ÂÍU-S-P.
(a) Enlist the functions of the liver.

OR

(b) Discuss the various steps involved in cholesterol biosynthesis.

38. (A) QøÍU-÷Põ-áß Áͺ-]øu ©õØ-Óz-÷uõk öuõ-hº-¦-øh¯ £i-{-ø»-PÒ ¯õøÁ ?
AÀ-»-x
(B) ÷Áva-\Æ-Åk £µ-ÁÀ öPõÒøP £ØÔ ÂÁ-›U-P-Ä®.
(a) What are the steps involved in glycogen metabolism ?

OR
(b) Describe chemiosmotic theory.

-o0o-

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