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TN 12th Question Paper 2024 Microbiology

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Page 1

TN PUBLIC EXAM

QUESTION
PAPER
2024

Page 2

No. of Printed Pages : 7
7462
!7462Microbiology! £vÄ Gs
Register Number

PART - III
~sq°›¯À / MICROBIOLOGY
( uªÌ ©ØÖ® B[Q» ÁÈ / Tamil & English Version)

Põ» AÍÄ : 3.00 ©o ÷|µ® ] [ ö©õzu ©v¨ö£sPÒ : 70

Time Allowed : 3.00 Hours ] [ Maximum Marks : 70

AÔÄøµPÒ : (1) AøÚzx ÂÚõUPЮ \›¯õP £vÁõQ EÒÍuõ GߣuøÚ \›£õºzxU
öPõÒÍÄ®. Aa_¨£vÂÀ SøÓ°¸¨¤ß AøÓU PsPõo¨£õÍ›h®
EhÚi¯õPz öu›ÂUPÄ®.
(2) }»® AÀ»x P¸¨¦ ø©°øÚ ©mk÷© GÊxÁuØS®,
AiU÷PõikÁuØS® £¯ß£kzu ÷Ásk®. £h[PÒ ÁøµÁuØS
ö£ß]À £¯ß£kzuÄ®.
(3) ÷uøÁ¯õÚ Ch[PÎÀ £h[PÒ ÁøµP.
Instructions : (1) Check the question paper for fairness of printing. If there is any lack of fairness,
inform the Hall Supervisor immediately.
(2) Use Blue or Black ink to write and underline and pencil to draw diagrams.
(3) Draw diagrams wherever necessary.

£Sv & I / PART - I
SÔ¨¦ : (i) AøÚzx ÂÚõUPÐUS® Âøh¯ÎUPÄ®. 15x1=15

(ii) öPõkUP¨£mkÒÍ |õßS ©õØÖ ÂøhPÎÀ ªPÄ® Hئøh¯
Âøhø¯z ÷uº¢öukzxU SÔ±mkhß Âøh°øÚ²® ÷\ºzx
GÊuÄ®.
Note : (i) Answer all the questions.

(ii) Choose the most appropriate answer from the given four alternatives and write
the option code and the corresponding answer.

[ v¸¨¦P / Turn over

Page 3

7462 2

1. ÷£ì Põßm-µõìm ~s-÷nõU-Qø¯ Ps-k-¤-iz-u-Áº ¯õº ?
(A) â¯õºä ìm÷µõUì (B) µõ-£ºm ÷Põa
(C) Aö»U-éõs-hº ¨öÍ®-ª[ (D) ¤›mì öéº-ÛU
Who invented Phase Contrast microscope ?
(a) George Strokes (b) Robert Koch
(c) Alexander Fleming (d) Frits Zernike

2. ¦÷µõU-÷P-›-÷¯õm-P-ÎÀ J¸ SÑU-÷Põì ‰»U-T-Óõ-Úx BU-ê\-÷ÚØ-Ó® Aøh¢x
EØ-£zv ö\´-²® ATP &°ß Gs-oUøP __________.
(A) 34 (B) 38 (C) 30 (D) 36
The number of ATP molecules generated from one molecule of glucose oxidized in
prokaryotes __________.
(a) 34 (b) 38 (c) 30 (d) 36

3. •uß-•-u-¼À S÷Íõ-Û[ öuõ-ÈÀ-~m-£z-v-ÚõÀ E¸-ÁõU-P¨-£mh ©µ-£-q »[S :
(A) -£õ-¼ (B) ÷å¼ (C) Áõ-¼ (D) hõ-¼
First genetically produced animal by cloning technique is __________.
(a) Bally (b) Shally (c) Vally (d) Dolly

4. En-ÂÀ ~s-q-°-›-PÒ Áͺ-Á-uØ-Sz ÷uøÁ-¯õÚ SøÓ¢-u-£m\ aw __________ BP
C¸UP ÷Ás-k®.
(A) 0.78 (B) 0.99 (C) 0.50 (D) 0.86
The minimum value of aw for the growth of the micro-organisms in foods should be
around __________.
(a) 0.78 (b) 0.99 (c) 0.50 (d) 0.86

5. ¤ß-Á-¸-Á-Ú-ÁØ-ÔÀ G¢u ÷Áv¨-ö£õ-¸Ò Fk-¸-Ä® BØ-ÓÀ AØ-Óx ?
(A) Gz-v-¼ß BU-øé-k (B) ¥ÚõÀ
(C) ¥m-hõ ¦÷µõ-ø£-÷¯õ-»õU-÷hõß (D) A÷¯õ-iß
Which of the following chemical lack penetrating power ?
(a) Ethylene oxide (b) Phenol
(c) Beta-propiolactone (d) Iodine

6. ¤ß-Á-¸® ÷|õ´-P-ÐÒ ¤.].-â uk¨-§] G¢-÷|õ´US uk-¨£õØ-ÓÀ AÎU-Qß-Óx ?
(A) -Põ-»-µõ (B) ]¤-¼ì (C) i¨-w-›-¯õ (D) Põ-\-÷|õ´
B.C.G. Vaccine gives immunity against which of the following disease ?
(a) Cholera (b) Syphilis (c) Diphtheria (d) Tuberculosis

Page 4

3 7462

7. Gß-h«
- £
- õ îì-÷hõ-¼i
- U-PõøÁ ö£õ-¸z-u©
- m-iÀ R÷Ç öPõ-kU-P¨-£m-kÒÍ TØ-ÖP
- Î
- À
Gx \›-¯õ-Úx ?
(A) CøÁ ©»&-Áõ´ ÁÈ-¯õP Phz-u¨-£-k-Á-vÀ-ø»
(B) AuØS ]ìm {ø» CÀ-ø»
(C) ©Û-u ö£¸[-S-h-¼À m÷µõ-÷£õ-\õ´-k-PÒ ÁõÌ-Qß-Ó-Ú
(D) Ax ÷|õ-²s-hõU-Põ-x
Which of the following statement is true concerning Entamoeba histolytica ?
(a) It is not transmitted through faecal-oral route.
(b) It has no cystic stage.
(c) Trophozoites live in large intestine of human.
(d) It is non-pathogenic.

8. jÛ-¯õ £õº-÷£ __________ GÚ-Ä® AøÇU-P¨-£-k-Q-Ó-x.
(A) £õº-£ºì Cma (B) ÷\Ø-Ö¨-¦s
(C) ÷Pß-i-i-¯õ-êì (D) Bß-÷Põ-ø©U-÷Põ-]ì
Tinea Barbae is also called as __________.
(a) Barber’s itch (b) Athlete’s foot
(c) Candidiasis (d) Onchomycosis

9. ö£Û-]-¼ß EØ-£z-vUS ÷\ºU-P¨-£-k® •ß-÷Úõi __________.
(A) øíi-÷µõ-S-÷Íõ-›U Aª-»® (B) ]m-›U Aª-»®
(C) ¤øÚ-°À A]m-iU Aª-»® (D) hõº-hõ-›U Aª-»®
The precursor used in Penicillin production is __________.
(a) Hydrochloric acid (b) Citric acid
(c) Phenyl acetic acid (d) Tartaric acid

10. ¤ß-Á-¸-Á-Ú-ÁØ-ÔÀ uÁ-Óõ-P¨ ö£õ-¸¢-v-²ÒÍ Cøn-ø¯U Ps-h-Ô-P.
(A) ÁøP III - uk¨-£õØ-ÓÀ Tm-h-øÚ-Ä
(B) ÁøP I - A÷hõ-¤
(C) ÁøP IV - ©õß-hõUì Gvº-Â-øÚ
(D) ÁøP II - Bº-uì Gvº-Â-øÚ
Identify the mismatched pair from the following :
(a) Type III - Immune complex
(b) Type I - Atopy
(c) Type IV - Mantoux reaction
(d) Type II - Arthus reaction

[ v¸¨¦P / Turn over

Page 5

7462 4

11. ¦µu EØ-£z-vø¯ __________ AkUS {Öz-x-Q-Ó-x.
(A) UAG (B) UGA
(C) UAA (D) ÷©Ø-Psh AøÚz-x®
__________ sequence terminates protein synthesis.
(a) UAG (b) UGA
(c) UAA (d) All of the above

12. öPõ_ ©Ø-Ö® Eso ‰»® £µ-Ä® øÁµì-P-ÐUS J¸ Euõ-µ-n® __________ BS®.
(A) ]U-SßSß-¯õ øÁµì (B) öh[S øÁµì
(C) Ga.-I. øÁµì (D) L÷£Í øÁµì
__________ is an example for mosquito-borne and tick borne viruses.
(a) Chikungunya virus (b) Dengue virus
(c) HIV virus (d) Flavi virus

13. Dìm ÷£õßÓ §gø\ GÚ AøÇU-P¨-£-k-Áx __________.
(A) \õU-P-÷µõ-ø©-]ì (B) ÷Pß-i-hõ
(C) Bì-£º-âÀ-»ì (D) Q›¨-÷hõ-PõU-Pì
__________ is called yeast like fungi.
(a) Saccharomyces (b) Candida
(c) Aspergillus (d) Cryptococcus

14. ShØ-Põ´a-\ø» HØ-£-kz-x-Áx __________.
(A) i›¨-÷£õ-Û-©õ £À-¼-h® (B) Göå-›-]-¯õ ÷Põ-ø»
(C) \õÀ-÷©õ-öÚÀ-»õ øh¤ (D) ¨-›-÷¯õ Põ-»-÷µ
Enteric fever is caused by __________.
(a) Tryponema pallidum (b) Escherichia coli
(c) Salmonella typhi (d) Vibrio cholerae

15. ªPa-]-Ô¯ øÁµ-êØS J¸ Euõ-µ-n® __________ BS®.
(A) ÷µ¥ì øÁµì (B) £õUì øÁµì
(C) HIV øÁµì (D) £õº-÷Áõ øÁµì
__________ is an example for the smallest virus.
(a) Rabies virus (b) Pox virus
(c) HIV virus (d) Parvo virus

Page 6

5 7462

£S-v & II / PART - II
SÔ¨¦ : GøÁ- ÷ ¯- Ý ® BÖ ÂÚõU- P - Ð US Âøh- ¯ - Î U- P - Ä ®. ÂÚõ Gs 24 &US
Pm-hõ-¯-©õP Âøh-¯-ÎU-P-Ä®. 6x2=12
Note : Answer any six questions. Question No. 24 is compulsory.

16. Bs-i-ö\¨-iU – Áøµ-¯-ÖU-P-Ä®. Gkz-xU-Põmk u¸-P.
Define Antiseptic. Give an example.

17. DNA Á›-ø\¨-£-kz-x-uÀ •øÓ-P-øÍU TÖ-P.
State the methods of DNA sequencing.

18. EøÓ-¯-øÁzx Põ-¯-øÁz-uÀ Gß-ÓõÀ GßÚ ?
What is called freeze drying ?

19. ¦Ñµ-ö\ßm ~s-÷nõU-Q-°ß £¯ß-PøÍ GÊ-x-P.
Write the applications of fluorescent microscopy.

20. ö|U› xPÒ-PÒ – Áøµ-¯-ÖU-P-Ä®.
Define - Negribodies.

21. ½è-÷©-Û-¯õ ÷hõ-÷Úõ-Áõ-øÚ-°ß ¨÷µõ-÷©ì-i-÷Põm {ø»-°ß £h® Áøµ¢x
£õ-P[-PøÍU SÔU-P-Ä®.
Draw the diagram of a promastigote form of Leishmania donovani and label the parts.

22. Phz-v-P-Îß ÁøP-PÒ ¯õøÁ ?
What are the types of Vectors ?

23. \¢-uº¨-£-Áõu ø©U-÷Põ-êì Gß-ÓõÀ GßÚ ?
What is opportunistic mycosis ?

24. §m- h ¨- £ mh uõøh ÷|õø¯ Es- h õU- S ® E°- › EØ- £ zv ö\´- ² ® |a- _ U- P - Î ß
ö£¯º-PøÍ GÊ-x-P.
Write the names of the toxins produced by the organism causing lock jaw disease.

[ v¸¨¦P / Turn over

Page 7

7462 6

£S-v & III / PART - III
SÔ¨¦ : GøÁ- ÷ ¯- Ý ® BÖ ÂÚõU- P - Ð US Âøh- ¯ - Î U- P - Ä ®. ÂÚõ Gs 33 &US
Pm-hõ-¯-©õP Âøh-¯-ÎU-P-Ä®. 6x3=18

Note : Answer any six questions. Question No. 33 is compulsory.

25. ö|õ-vz-uÀ ÷©À-÷|õUS •øÓU-S®, ö|õ-vz-uÀ RÌ-÷|õUS •øÓU-S® Cøh-÷¯-²ÒÍ
÷ÁÖ-£õ-k-PøÍ Am-h-Á-øn¨-£-kz-x-P.
Tabulate the differences between upstream and downstream fermentation process.

26. Kº E¯º-{ø» Phz-v-°ß £s-¦-PøÍ GÊx-P.
Mention the characteristics of an Ideal Vector.

27. u°-›ß £¯ß-PøÍ GÊ-x-P.
Write the uses of Curd.

28. i¨-w-›-¯õ-ÂØS ÷©Ø-öPõÒ-Ю ÷|õ´ uk¨¦ £ØÔ GÊ-x-P.
Write about the prophylaxis for Diphtheria.

29. ]U-SßSß-¯õ øÁµì £ØÔ GÊ-x-P.
Write about Chikungunya virus.

30. PÖ¨¦ }º Põ´a-\À Gß-ÓõÀ GßÚ ?
What is black water fever ?

31. öẮ SÇõ´ ÷\õ-uøÚ £ØÔ ]Ö SÔ¨¦ Áøµ-P.
Write a short note on Germ Tube test.

32. MBC ©Ø-Ö® MIC ÷\õ-uøÚ Gß-ÓõÀ GßÚ ?
What is meant by MBC and MIC test ?

33. E°› ÂøÚ-³U-Q-¯õP ö\¯À-£-k-Áx Gx ? Auß £¯ß-PøÍ GÊ-x-P.
Which is acting as a biocatalyst ? Mention its uses.

Page 8

7 7462

£S-v & IV / PART - IV
SÔ¨¦ : AøÚz-x ÂÚõU-P-ÐU-S® Âøh-¯-ÎU-P-Ä®. 5x5=25
Note : Answer all the questions.

34. (A) SEM ©Ø-Ö® TEM &ªØ-S Cøh÷¯ EÒÍ ÷ÁÖ-£õ-k-PøÍ GÊ-x-P.
AÀ-»-x
(B) QøÍ-Põ-øÍ-]ì £õøu £ØÔ ÂÁ-›U-P-Ä®.
(a) Write the differences between SEM and TEM.
OR
(b) Explain Glycolysis pathway.

35. (A) ö£Û-]-¼ß EØ-£z-v-°À EÒÍ £À-÷ÁÖ {ø»-PøÍ £hz-x-hß ÂÁ-›U-P-Ä®.
AÀ-»-x
(B) En-Ä £u¨-£-kz-x® •øÓ-P-øÍ ÂÁ-›U-P-Ä®.
(a) Explain the various phases of Penicillin production with diagram.
OR
(b) Describe the methods of Food Preservation.

36. (A) â¯õº-i-¯õ »õ®-¤-¼-¯õ-Âß ÁõÌUøP _ÇØ-]ø¯ ÂÁ-›U-P-Ä®.
AÀ-»-x
(B) öí¨-£-øh-iì B øÁµì Aø©¨ø£ ÂÁ-›U-P-Ä®.
( a) Write in detail about the life cycle of Giardia lamblia.
OR
(b) Explain the structure of Hepatitis B virus.

37. (A) ÷|µ-i Gø»\õ-ÂøÚ £hz-x-hß Â›-ÁõP ÂÁ-›U-P-Ä®.
AÀ-»-x
(B) ©Ö-÷\ºUøP DNA öuõ-ÈÀ-~m-£z-vÀ EÒÍ {ø»-PøÍ ÂÁ-›U-P-Ä®.
(a) Explain the Direct ELISA with diagram.
OR
(b) Explain the stages involved in recombinant DNA technology.

38. (A) ¥ÚõÀ ÷Põ-G-¤-ö\ßm ÷\õ-u-øÚø¯ ÂÁ-›U-P-Ä®.
AÀ-»-x
(B) vµõmø\ öPõzx ÷£õßÓ Aø©¨-¦-øh¯ £õU-j-›-¯õ EØ-£zv ö\´-²® |a-_U&
-PøÍ¨ £ØÔ ÂÁ-›U-P-Ä®.
(a) Explain the Phenol Coefficient test.
OR
(b) Explain about the toxins produced by the bacteria having grape like cluster appearance.

-oOo-

[ v¸¨¦P / Turn over

Page 9

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Document Details

Board / OrgTamil Nadu Board
ExamClass 12
TypeQuestion Paper
Pages9
Updated30 Apr 2026