TN 12th Question Paper 2023 Bio-Chemistry

Tamil Nadu
State Board

2023
QUESTION
PAPER

No. of Printed Pages : 8
6663
!6663BioChemistry! £vÄ Gs
Register Number

PART - III
E°º ÷Áv°¯À / BIO-CHEMISTRY
(uªÌ ©ØÖ® B[Q» ÁÈ / Tamil & English Version)

Põ» AÍÄ : 3.00 ©o ÷|µ® ] [ ö©õzu ©v¨ö£sPÒ : 70

Time Allowed : 3.00 Hours ] [ Maximum Marks : 70

AÔÄøµPÒ : (1) AøÚzx ÂÚõUPЮ \›¯õP £vÁõQ EÒÍuõ GߣuøÚ \›£õºzxU
öPõÒÍÄ®. Aa_¨£vÂÀ SøÓ°¸¨¤ß AøÓU PsPõo¨£õÍ›h®
EhÚi¯õPz öu›ÂUPÄ®.
(2) }»® AÀ»x P¸¨¦ ø©°øÚ ©mk÷© GÊxÁuØS®
AiU÷PõikÁuØS® £¯ß£kzu ÷Ásk®. £h[PÒ ÁøµÁuØS
ö£ß]À £¯ß£kzu ÷Ásk®.
(3) ÷uøÁ¯õÚ ChzvÀ Áøµ£h® ©ØÖ® \©ß£õkPøÍz u¸P.
Instructions : (1) Check the question paper for fairness of printing. If there is any lack of
fairness, inform the Hall Supervisor immediately.
(2) Use Blue or Black ink to write and underline and pencil to draw
diagrams.
(3) Draw diagrams and write equations wherever necessary.

£Sv & I / PART - I

SÔ¨¦ : (i) AøÚzx ÂÚõUPÐUS® Âøh¯ÎUPÄ®. 15x1=15

(ii) öPõkUP¨£mkÒÍ ©õØÖ ÂøhPÎÀ ªPÄ® Hئøh¯ Âøhø¯z
÷uº¢öukzxU SÔ±mkhß Âøh°øÚ²® ÷\ºzx GÊuÄ®.

Note : (i) Answer all the questions.

(ii) Choose the most appropriate answer from the given four alternatives
and write the option code and the corresponding answer.

[ v¸¨¦P / Turn over

6663 2

1. RBC &UPÎÀ __________ }¸hß ÂøÚ£mk Põº£õÛU Aª»zøuz u¸QÓx.
(A) HCO−
3 (B) CO2 (C) CO 23− (D) CO
In RBCs __________ reacts with water forming carbonic acid.
CO 23
− −
(a) HCO 3 (b) CO2 (c) (d) CO

2. __________ ö\ÀPÒ HCl &I _µUQßÓÚ.
(A) _Áºa ö\ÀPÒ (B) •ußø©a ö\ÀPÒ
(C) \Îa ö\ÀPÒ (D) G &ö\ÀPÒ
HCl is secreted by __________.
(a) Parietal cells (b) Chief cells
(c) Mucosal cells (d) G cells

3. |õͪÀ»õ ©ØÖ® |õÍ•ÒÍ _µzuÀ BQ¯ Cµsk ö\¯À£õkPøͲ® öPõsh
EÒÐÖ¨¦ :
(A) ¤zu¨ø£ (B) Cøµ¨ø£ (C) Pøn¯® (D) PÀ½µÀ
The organ that functions as both exocrine and endocrine :
(a) Gall bladder (b) Stomach (c) Pancreas (d) Liver

4. QøÍUPõ¼]ì {PÌÂß CÖv ÂøÍö£õ¸Ò :
(A) A]møhÀ CoA (B) ]m÷µm
(C) »õU÷hm (D) ø£¸÷Ám
The end product of glycolysis is __________.
(a) Acetyl CoA (b) Citrate
(c) Lactate (d) Pyruvate

5. iµõßì Aª÷ÚØÓ® Gߣx :
(A) J¸ Rm÷hõ Aª»zv¼¸¢x Aª÷Úõ öuõSvø¯ ©õØÔ J¸ Aª÷Úõ
Aª»zøu E¸ÁõUSuÀ
(B) J¸ Rm÷hõ Aª»zvÀ Rm÷hõ öuõSvø¯ ÷\ºzx Aª÷Úõ Aª»®
E¸ÁõUSuÀ
(C) J¸ Rm÷hõ Aª»® ©ØÖ® J¸ Aª÷Úõ Aª»zvØQøh÷¯ Aª÷Úõ
öuõSvPÒ £›©õØÓ® Aøhuø» EÒÍhUQ¯x
(D) ÷©ØPskÒÍ AøÚzx®
Transamination involves :
(a) transfer of amino groups from a keto acid to form an amino acid
(b) addition of keto groups to keto acid to form an amino acid

(c) exchange of amino groups between a keto acid and an amino acid
(d) all the above

3 6663

6. Põº£©õ°À £õì÷£m ]¢u÷hì -II __________ CÀ Põn¨£kQÓx.
(A) ø©m÷hõPõsi›¯õÂÀ J¸ £Sv¯ÍÄ ©ØÖ® ø\÷hõ\õ¼À £Sv²®
Põn¨£kQÓx
(B) ø©m÷hõPõsi›¯õ
(C) EmP¸
(D) ø\÷hõ\õÀ
Carbamoyl phosphate synthetase-II is present in the __________.
(a) Partly mitochondria and partly in the cytosol
(b) Mitochondria
(c) Nucleus
(d) Cytosol

7. ö\À \ÆÂØS __________ J¸ |a\õS®.
(A) ø»÷\õö»]vß (B) ö»]vß
(C) i›¨]ß (D) ö\L¨£õ¼ß
__________ is highly toxic to cell membranes.
(a) Lysolecithin (b) Lecithin
(c) Trypsin (d) Cephalin

8. DNA &¾ÒÍ uPÁø» __________ ö\¯À •øÓ°ß ‰»©õP RNA &ÂØS ©õØÓ
•i²®.
(A) ©õØÖ £iö¯kzuÀ (B) Cµmi¨£õuÀ
(C) E°µq ö©õÈ ©õØÓ® (D) £iö¯kzuÀ
The information in the DNA can be copied to RNA by a process called __________.
(a) reverse transcription (b) replication
(c) translation (d) transcription

9. ï÷©õ¥¼¯õ C &ø¯ E¸ÁõUS® Põµo __________.
(A) Põµo XI (B) Põµo VIII (C) Põµo V (D) Põµo VII
Hemophilia C is caused by :

(a) Factor XI (b) Factor VIII (c) Factor V (d) Factor VII

[ v¸¨¦P / Turn over

6663 4

10. G¢u ö|õv SøÓ£õk Põµn©õP Põ»U÷hõ^ª¯õ E¸ÁõQÓx ?
(A) Põ»U÷hõì -1- £õì÷£m ³›øhÀ iµõßìö£÷µì
(B) SÐU÷PõøP÷Úì
(C) £õì÷£õSÐU÷Põª²÷hì
(D) Põ»U÷hõøP÷Úì
The deficiency of which enzyme causes galactosemia :
(a) galactose-1-phosphate uridyltransferase
(b) glucokinase
(c) phosphoglucomutase
(d) galactokinase

11. BUêá÷ÚØÓ £õì£õ›÷»ØÓzvß Cønz uk¨£õß :
(A) Aø\k (B) DNP (C) öµõmi÷Úõß (D) DTT
An uncoupler of oxidative phosphorylation is :
(a) azide (b) DNP (c) Rotenone (d) DTT

12. J¸ ö|õv ‰»UTÔÚõÀ, J¸ Â|õi ÷|µzvÀ Âøͨ ö£õ¸ÍõP ©õØÓ¨£k®
ÂøÚ¨ö£õ¸Ò ‰»UTÖPÎß GsoUøP __________ GßÓøÇUP¨£kQÓx.
(A) AvP£m\ ÂøÚ÷ÁP® (B) ÂøÚ÷ÁP Gs
(C) Km (D) EP¢u Gs
The number of molecules of substrate converted into product per enzyme molecule
per second is called the __________.
(a) Maximum reaction rate (b) Turnover number
(c) Km (d) Optimum number

13. ysh¨£mh ö£õ¸¢xuÀ ©õv› öPõÒøPø¯ E¸ÁõUQ¯Áº __________.
(A) ÷Põè»õsm (B) iU\õß
(C) ø©UP¼ì ö©ßhß (D) ¤èåº
Induced fit model was proposed by __________.
(a) Koshland (b) Dixon
(c) Michaelis Menten (d) Fischer

14. ^®£õ¼À EÒÍ Bßi£õi __________.
(A) IgM (B) IgG (C) IgE (D) IgA

Antibody present in Colostrum is __________.
(a) IgM (b) IgG (c) IgE (d) IgA

5 6663

15. Rh Põµoø¯ PshÔ¢uÁº ¯õº ?
(A) PõºÀ »õshìøhÚº ©ØÖ® ÷Põa
(B) PõºÀ »õshìøhÚº ©ØÖ® öÁ´Úº
(C) GmÁºk öáßÚº
(D) ¿°ì £õìhº
Who discovered Rh factor ?
(a) Karl Landsteiner and Koch
(b) Karl Landsteiner and Weiner
(c) Edward Jenner
(d) Louis Pasteur

£Sv & II / PART - II
SÔ¨¦ : H÷uÝ® BÖ ÂÚõUPÐUS Âøh¯ÎUPÄ®. ÂÚõ Gs 24 &US
Pmhõ¯©õP Âøh¯ÎUPÄ®. 6x2=12
Note : Answer any six questions. Question No. 24 is Compulsory.

16. uõ[PÀ Pøµ\ÀPÒ – Áøµ¯ÖUPÄ®.
Define buffers.

17. öÁÆ÷ÁÖ ÁøP¯õÚ EªÌ}º _µ¨¤PøÍ AÁØÔß Aø©Âh[PÐhß
SÔ¨¤kP.
Mention the different types of salivary glands along with its location.

18. NADH ©ØÖ® NADPH BQ¯ÁØÔØQøh÷¯¯õÚ ÷ÁÖ£õk ¯õx ?
What is the difference between NADH and NADPH ?

19. Aª÷Úõ öuõSv }UP® GßÓõÀ GßÚ ?
What is deamination ?

20. öPõʨ¦ Aª»[PÒ ø©m÷hõPõsj›¯õÂØS Phzu¨£kuø»¨ £ØÔ GÊxP.
Write about the transport of fatty acids into the mitochondria.

21. £õ¼©÷µì \[Q¼z öuõhº ÂøÚ¯õUQ £ØÔ _¸UP©õP GÊxP.

Write a short note on polymerase chain reaction.

[ v¸¨¦P / Turn over

6663 6

22. Q꼀 ø©¯® – Áøµ¯ÖUPÄ®.
Define active site.

23. ÷|õ°¯À – Áøµ¯ÖUPÄ®.
Define epidemiology.

24. ö|õvz ukzuÀ GßÓõÀ GßÚ ? Auß ÁøPPøÍ GÊxP.
What is Enzyme Inhibition ? Write their types.

£Sv & III / PART - III
SÔ¨¦ : H÷uÝ® BÖ ÂÚõUPÐUS Âøh¯ÎUPÄ®. ÂÚõ Gs 33 &US
Pmhõ¯©õP Âøh¯ÎUPÄ®. 6x3=18
Note : Answer any six questions. Question No. 33 is Compulsory.

25. øh\õUPøµkPÒ GßÓõÀ GßÚ ? ]Ö Sh¼À Põn¨£k® øh\õUPøµkPøͨ
£mi¯¼kP.
What are disaccharides ? List the disaccharides in the small intestine.

26. i›¨÷hõ÷£ß GÆÁõÖ {¯õ]ÚõP ©õØÓ¨£kQÓx ?
How is Tryptophan converted into niacin ?

27. ö\À\ÆÂß vµÁz ußø©ø¯ £õvUS® ‰ßÖ •UQ¯ PõµoPÒ ¯õøÁ ?
What are the three major factors that can influence fluidity of a cell membrane ?

28. ÷Põ› _ÇØ] £ØÔ ]Ö SÔ¨¦ ÁøµP.
Give a short note on Cori Cycle.

29. öPõ»ìiµõ¼ß •UQ¯ ö\¯À£õkPøÍ GÊxP.

Write the important functions of cholesterol.

7 6663

30. ¦÷µõ÷P›÷¯õiU ©ØÖ® ³÷P›÷¯õiU £iö¯kzu¼À EÒÍ ÷ÁÖ£õkPøÍ
GÊxP.
Write the differences between Prokaryotic and Eukaryotic in transcription.

31. ÁõßQŸU ÷|õ´UPõÚ ö£õxÁõÚ AÔSÔPøͨ £ØÔ GÊxP.
Write about the common symptoms of Von-Gierke disease.

32. ø©m÷hõPõsm›¯õÂß EÒÍø©¨ø£ ÂÍUSP.
Explain the structure of mitochondria.

33. øÁhõÀ ÷\õuøÚ¨ £ØÔ GÊxP.
Write about ‘Widal Test’.

£Sv & IV / PART - IV
SÔ¨¦ : AøÚzx ÂÚõUPÐUS® Âøh¯ÎUPÄ®. ÷uøÁ¯õÚ Ch[PÎÀ £h®
ÁøµP. 5x5=25
Note : Answer all questions. Draw the diagrams wherever necessary.

34. (A) J¸ \ÆÂß ¦µu Cø¯¦ £ØÔ ÂÍUSP.
AÀ»x
(B) Cµzu ÁÈ ©ØÖ® ö\ÀÁÈ ÷|õ´ uøhUPõ¨ø£ J¨¤kP.
(a) Write about protein composition of membrane.
OR
(b) Compare the events of humoral and cell mediated immunity.

35. (A) ÷£õmiz ußø©²ÒÍ ukzuÀ GÝ® öPõÒøPø¯ ÂÁ›UPÄ®.
AÀ»x
(B) AÀ¤Û\zvß ÁøPPøÍ ÂÁ›UPÄ®.
(a) Explain the concept of Competitive Inhibition.

OR
(b) Describe the types of Albinism.

[ v¸¨¦P / Turn over

6663 8

36. (A) öPõʨ¦ Aª» BU]á÷ÚØÓ® £ØÔ ÂÍUSP.
AÀ»x
(B) ©µ¤¯¼À Akzu uø»•øÓ Á›ø\ Aø©¨¦ PshÔuÀ (NGS) öuõÈØ
~m£[PÎß £À÷ÁÖ £¯ßPøÍ ÂÍUSP.
(a) Give an account on oxidation of fatty acids.
OR
(b) Explain the different applications of the Next Generation Sequencing (NGS)
technologies in genomics.

37. (A) TCA _ÇØ]°À EÒÍ £i{ø»PøÍ ÂÁ›UPÄ®.
AÀ»x
(B) ³›¯õ _ÇØ] ©ØÖ® Auß •UQ¯zxÁzvøÚ¨ £ØÔ Â›ÁõP ÂÍUSP.
(a) Describe the steps involved in TCA cycle.
OR
(b) Elaborate on Urea cycle and its significance.

38. (A) E¯º BØÓÀ ÷\º©[PÒ £ØÔ ÂÍUSP.
AÀ»x
(B) Cøµ¨ø£U ShÀ íõº÷©õßPøͨ £ØÔ ÂÍUSP.
(a) Explain about high energy compounds.
OR
(b) Explain the Gastrointestinal hormones.

-o0o-