KUET 2022 Question Paper M.Sc. Biochemistry

FOR KUET EXAM PREPARATION

KUET 2022
Question Paper · M.Sc.
Biochemistry
EXAM YEAR TYPE SUBJECT

KUET 2022 Question Paper M.Sc. Biochemistry

Notes · Sample Papers · Previous Year Papers · Mock Tests

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Sr, No.

ENTRANCE TEST.2O22
SCHOOL OF' BIOLOGICAL SCIENCES

m
BIOCHEMISTRY
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r60 Question Booklet Series I

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TotalQuestions I

170 Minutes
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TimeAllowed

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Roll No. :

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Instructions for Candidates :

Entrance Roll Number in
Test the space prov ided at the top of this page of euestion Booklet
fill up
and necessary information in *re
the spaces provided on the O'IMR Ans;e1 Sheat.

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makrng entries in the original copy. candidate shouid ensure thai thi two copies are alisned DroDerlv
so thar the entries made in rhe original copy against each item are exacrly cbpied in Lhi carididate's
uopy.
3. All entries inthe oMRAnswer sheet, including answe^ to questions, are to be recorded in the original

m arnong the options A, B, C and D and
Copy only.

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4. Choose lhe conect /.most appropriate response for each question

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darl(en the cucleol the appropnate response completely. The incomplete darkened circie isnot correcrly

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T rhere wili be 'Negative Marking' for wrong answers. Each wong answer will lead to rhe deduction
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11. Rough work, ifant should be done on the blank sheets provided with the question booklet.

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be and be or case

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that your oMR Answer sheet has been signed by the Invigilator and the candidate himselfl
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herself,
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l. Which ofthe following is inconect ? 5. The fi$t step in photosynthesis is :
(A) A pi bond is formed after sigma bond (A) Formation ofreduced carbon compounds
formation takes place
(B) Rotation of orbitals is ceased after the pi (B) The excitement ofan elechon ofchloroph)
bond is formed by a photon of light

(C) A pi bond is more stable than a sigma boad (C) FormationofAlP
due to multiple contaots ofthe orbitals
(D) Atl alkanes, alkenes, and alkynes exhibit (D) Splitting ofa water molecule
sigmabondformation 6. The dark reaction is also called :
Following elements are arranged in increasing
(A) Bios)'ntheticphase
order oftheir electxonegativity Pickup tlre conect
order of elements aranged bY their (B) Blackman'sreaction
elechonegativify : (C) Calvin cycle
(A) F<S<P<N<O
(D) All ofthe above
(B) P<S<N<O<F
(c) N<o<F<P<S 7. SI unit ofentropy is :

(D) N<P<S<F<O (A) J.
3. A pair ofmolecules that axe mirror images ofeach
other but cannot be superimposed one upon the
(B) vs
other are called : . (c) J
(A) Enantiomers
(D) vc
(B) Confomers
(C) Diastereomers 8' The most abundart enzyme on eadh - Rubis

(D) Positional isomers stands for :

4. Pick up the weakest and the strcngest bonds : (A) Ribose- 1,5 -bisphosphate carboxyla
i. Ionic bonds oxygenase
ii. Metallic bonds
iii. Covalentbonds @) Ribulose-1,5-bissulplate carboxyla
iv. van der Waals forces oxygenase

v. Hy&ogenbold (C) fubulose- I ,5 -bisphosphate carboxylt
(A) v and i oxygemse
(B) ii and v
(C) iv and i @) Rubisco- i ,5 -bispho sphate reductr
oxyge0ase
(D) iv and iii

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as 9. Provide the conect match of the statements m
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ll. aWhich of the following contributes to global
ColumnAfiom Column B below :
warming ?
ColumnA Colurrn B
(A) Methane
i. The most common way
for nitogen fixation
@) Carbon dioxide
(C) Nitrous oxide

om
is by a. Denitrification

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ii. Organic nitrogen is (D) All ofthe aboye
converted backoto
c. e m
inorganicm s
12. Among the following four copper-dependents

agairut aenzlme
s e nitrogen like g l
la throughttrc a
enzlmes, thee are plac€d the class

g
aprccess of
ammonirun, they belong to, pick the which
up assigted
one is
b. Nitrogen oxides to tlre tlTong class ofenzymes ?
iii, Eutrophication can (A) Oidoreductase - ascorbate oxidase
cause an inqease in c. Decay (B) Monooxygenase - multicopper feroxidase
iv. Which process releases
(C) Electontransferring-cltocbrome c oxidase
dinitrogen gas (.,1r)
(D) Oxidase - Laccase

o m The pathogen ofCOVID-I9
back into the d. Fixed nihogen

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13. is disease :

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(Anxmoniun)

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v. (A) S€vere acute respiratoly syndrome
a
add e. Nitrogen-fixing
Synthetic ferti.lizers

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coronavirus 1
bacteria
vi. Which ofthe following (B) South Asian respiratory syndrome
is a component ofacid f, Haqnful algal coronavirus I
min blooms (C) Severe aaute respiratory syndrome
(A) i-e, ii-c, iii-f, iv-a, v-d, vi-b coronavirus 2
(B) i-c, ii-e, iii-{ iv-4 v-d, vi-b (D) South Asian respiratory syndrome

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(C) i-e, ii-c, iii-a, iv-f, v-d, vi-b

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coronavirus 2

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c. o Which ofthe
@) i-e, ii-c, iii-f, iv-4 v-b, vi-d
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14. Which ofthe following types oflaccircs arc being

m gastrointestinal toxicity s e
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10. (IIg, metals

e
Pb, Cr, Cd andAs) cause
tested or used against Covid- 19 disease ?

l as g RNA vaccine
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?
(A) Messenger
ag
(A) Hg Cr and
(B) Vector vaccines
@) Hg, Cr Pb and

(C) Hg, Pb, Cr, Cd andAs (C) Prctein component vaccine
(D) Hg, Pb, Cr and Cd (D) All ofthe above

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15. D tpe amino acids are found in: 20. The enzyme rcsponsible for the removal of
(A) Nervous systern and endocrine system supercoiling in replicating DNA ahead of the
(B) The nervous system, endocrine system and replication fork is :
bacterial cell wall (A) Primase
(C) Bacterial cell wall (B) DNA polymense
(D) Neryous systcm
(C) Helicase
16. When NADH reduces plruvate, the product is :
(D) None ofthe above
(A) Lactic acid
21' Compare the en4me class with tlle rcaction they
(B) Alcohol
cat^ltze',
(C) Dihydroxyac€tone
(D) Both d- and l-glYceraldehYde a. Oxidoreductases Group tansfer reactions

17. Which class of carbohydrates is considered b. Transferases ll. Hydrolysis reactions

notr-sugax ? c. Hydrolases lll Tmnsfer ofelectrons
(A) Monosaccharides d. Lyases Formation ofbods bY
(B) Disaccharides
condeosation reactions
(C) Polysaccharides
coupled to AIP clea\"ge
(D) Oligosaccharides
Isomelases Addition ofgroups to
18. Th€ net charge on a prot€in will be zero, positive
and negative when the pH of a solutiotr is : double bonds

(A) Above its pl, below its pl, and at its pl f. Ligases Transfer ofgroups with
resPectivelY in molecules
(B) At its pl, below its pl and above its pl
(A) a-i, b-ii, c-iii, d-iv, e-v, f-vi
resPectively
(C) At its pl, above its pl and below its pl (B) a-iii, b-i, c-ii, d-v, e-vi, f-iv
rgsPectivelY (C) a-iv, b-i, c-ii, d-v, e-vi, f-iii
(D) All the above statements arg incorect (D) a-iii, b'i, c-v, d-ii, e-vi, f-iv
19. Which of the following is the Chylomicron 22. Reversile inhibition can be :
component ?
(A) Competitive and uncompetitive
(A) Cholesterol
(B) Competitive only
(B) Triglycedde
(C) Apolipoprotein B48 (C) Uncompetitive only

@) All of the above (D) Competitive, uncompetitive and mixed
'a

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as 23. High levels ofacids phosphate are indicato$ of: 28. Which citric acid cycle a g
enzylne uses FAD+ ?
(A) Stomach cancer (A) Malatedehydrcgenase
(B) Prostate cancer (B) Succinatedehydrogenase
(C) Braintumour (C) Citrate slnthase

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@) None of the above (D) Alpha-Ketoglutaratedehy&ogenase

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29. Ribosomes are present on :
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24. Which ofthe following can bind to haem ?

m . (A) Endoplasmicrcticulum
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(A) Oxi€en

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@) Nuclearmembrane
(c) No ag
(B) Co
(C) Both ofthe above
(D) Both (A) and @) are inconect
(D) All ofthe above
30. Which ofthe following do not sharc similadties
25. Which ofthe following enzyme catallze the rate-
or are not linked to one another ?
limiting step in the pentose phosphate pathway ?
(A) Prokaryoticcell-chloroplast-mitochondria
(A) Tmnsketolase
m Endoplasmic leticulum-colgi aomplex-
(B) Betaoxidalion-Nucleus-Lysosome
(B) Glucose-6-P dehydrogenase
.c o(C)
e m
s
(C) Transaldolase
a
Trausporting vesicle
(D) Phosphogluconatedehydrogenase
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(D) Glycolysis-Urea cycle-Citric acid cycle
26. The urea cycle is linked to : 3t. Wbich of the following does Dot contain any
(A) Citric acid cycle membrane ?

@) Glycolysis (A) Ribosome
(C) Pentose Phosphate Pathway (B) Plant vacuole
(C) Endosome
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(D) Betaoxidation

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(D) Vesicle
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. to the linker DNA
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2'7. How manyAfP molecules are produccd in a citric

s e histones)
32. Which of the histones binds

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acid cycle for every glucose molecule ?

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(DNA that links two adjacent

a
?

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(A) H4
15
(B) H3
(c) 4
(c) IDA
(D) 2
(D) Hl

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molecular
structure has an 37' Two <lifferent proteins with the same
33. Beads-on-string (nucleosome) when run
weight trave$e different distances
averige diameter of : cold room The
together in a native PAGE in a
(A) 10 n possible reason is/are
(B) 15nm (A) The two proteins experience the diffelent
movement
(C) 20nn magnitude of resistance in their
as Possess different shaPes
(D) 25nm
the (B) The two ploteins possess different amno
Which of the following proteins recognize
acid sequences
the E-coli
origin of replication and is called
(C) They have no different interactions with
licencing factor ? polYacrylamide gel
(A) DnaA (D) All ofthe above
(B) DnaB of proteins'
38. For gel filtration chromatography
(C) DNAPollmerasel[ which ofthe following is true ?
(A) Large or elongated proteins enter the pores
(D) ToPoisomerase I
in the beads
of Marshall
35, What was the main limitation (B) Small proteins enter the pores in the beads
Nirenberg's findings on genetic code ?
(C) Large or elongated proteins elute ftom the
(A) Triplet concept ofa codon was missing bottom ofthe column later

(B) Compositions of codons werc not knolln (D) Small Poteins elute ftom the bottom ofthe
amino colwmfust
(C) The sequence ofcodons for differcnt
SDS'PAGE and gel
acids was not known 39' The movement of proteins in
filtrations can be described as
:

(D) None ofthe above
can
(A) Latger proteins follow the smaller proterns
36. Which ofthe post-translational modifications in both the resolving techniques
?
happento chromatin histones
(B) Snaller proteins follow the laryer proteirs
(A) MethYlation and acetylation in both the resolving tecbniques

(B) ADP-ribosylationandphosphorylation (C) Smaller protein will move fiIst in SDS-
PACE and later in gel filtation
(C) Gtvcosylation, SUMOylation and
ubiquitination
(D) Smauer protein will move latel in SDS-
PAGE and fust io gel filtration
(D) All oftbe above
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as 40. Which technique is used to
assay drug 44. The test
g
afor
concentration in plasma ?
clecking mean plasma glucose
concenhation over the previous
(A) IR spechoscopy 8- 10 weeks is :
(A) Fasting plasma glucose corcentration
(B) uvspectroscopy for h4'o
daYs
(c) Non-aqueous titration
(B) HaemoglobinAlc
(D) RIA
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41. whichsratemenvshordsgoodforElrsA?

las
[]
em both antigen and 45. Which diseases cause elevated SGOT
las
(A) Can be used to detect
antibody
g and car ag
and SGpT

(B) It is veryasensitive
in the blood ?
detect less than (A) Hepatitis A or B or C or
a nanograrn ofa protein chronic viral
hepatitis
(c) Enzyme-linked to an anti
body can be (B) cinhosis ofthe liver or liver
qonocloral orpolyclonal damage fiom
alcohol
(D) All ofthe above arc conect

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co or tne above
42. Fe in the hemoglobin is in a fenous jl] l:.::*.-*r*
. "ul
state and rhe tu)
46em
oxygel molecule binds at:
(A) 6d coordination site
l a s In which ofthe following clinical

g activity ofcreatine kinase not
conditions, the
a
.

(B) Its l"rcoordination site is seen ?

(c) 3'd coordination site (A) Muscular dysftophy
(D) 46 coordination site (B) Muscle disease
43 Which ofthe following is corect ? (c) Pancreatitis
(A) only 50% of the oxygen (D) Myocardial infarction
carried by

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ofa 47. which of the folloMng enzymes hydrolyses
lemoglobin can be released in

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absence

co pH changes to 7.2 only 40% ofits maltose m
pH
.
change in

e
alpha-l,4linftages in

s
glycogen starch and
leld
moxygen is released
to

e a
(B) when
s (A) Alpha-amylase g l
?

gl a a
a (C) Hydrogen
,
ions and
carbondioxide increases (B) sucrase
ofHaemoglobin
oxygen affinif
(c) Lactase
(D) Noneoftheabove
(D) _All ofthe above
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48. What is a xenobiotic ? 52. Match tle two colururs corectly :
(A) A nutient i Ilpe I Hypersensitivity 4. Transfi.rsion
(B) Metabolizable chemical substanaes but not reaction and

a nutrient hcmol]'tic disease

(c) Non-Metabolisabte and but can be used as ofa newbom are
anutrient its examples
(D) Metabolisablenutrient ll. D?€ tr H$ersensitivit b Involve Tr1 cells
r 49. tnnaie immunity does not hclude : lll Dpe m Result inArthus

(A) Aratomic and physiologic barders Hypersensitivity reaction

(B) Endocytic atrd phagocl'tic barriers fype IV d, Mediated by IgE

(C) Inflammatory balriels t{}?ersensitivity antibodies

(D) None ofthe above (A) i-4 iib, iiic and iv-d
50. Adaptive immune rcsponses are characteiized (B) i-a" ii-d, iii-b and iv-c
by, (C) i-d, ii-c, iii-a ard iv-b
i. Specificity (D) i-d, ii-a, iii-c and iv-b
ii. Diversity 53. A large quantity of a genome or a piece ofDNA
iii. Memory is needed for laboratory purposes. It can be
iv Selflnon-selfrecognition obtained by :
(A) i and ii (A) The growing large number ofcells in a cell
G) i, n and iii culhrc
(C) i, ii, iii and iv (B) Bycloning
P) ii, iii and iv (C) By poll'rnerase chain reaction
51. The major effector function/s that cnable (D) All ofthe above
antibodies to remove antigeru and kill pathogens
54. The type of restriction eDzyme used in IDNA
rs/ar€ :
technology is :
(A) OPsonization
(A) Type i
(B) Complement activation and ,antibody-
(B) Tlpe tr
dependent cell-mediated c)'totoxicity

(C) Both (A) and @)
(C) Typeltr
(D) Neither (A) nor @) (D) All ofthe above

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as 55. Which of the following is the mosr rmponant a g
58. Calculate the Gibbs ftee energy for the rcaction
discovery that led to the discovery ofrecombfuunt
of conversion ofAlp into ADp, at 293 Kelvin,
DNA tecbnologr ?
the change in enthalpy is 19.02 Kcal and
(A) Discovery that DNA is the genetic material the
(B) Discavery ofDNA struchne change in entropy is 90 cal per Kelvin :

(C) Deciphering ofgenetic code (A) 7.3 cal
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@) Discovery ofrestriction enzymes (B) -5.3 Kcal

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56. Choose the incorrect statement for yAC vecto$ : (C) 7.3 Kcal

e m
(A) The YAC molecu.le is approximately I 0 kb
l a s
s g
(D) -7.3 Kcal

g l
in size
a melting ofice into liquid water a example
aprokaryotic origin of replication
59. The
(B) It contains both yeast origin ofreplicatiol
is an
oftube rcactron.
and
(C) It doesn't contain the ampicillin_resistant (A) endergonic
geno (B) exergonic
@) It contains TEL sequence (C) exothemric
57. The heat given to an ideal gas in isothermal
@) endothermic
m
conditiols is us€d to :

o
.c (A) Formation
60. What is the reverse process ofNeutralizatron
(A) Inqease tempcratue ?

@) Do external work
m
e (B) Hydrctysis
l a s
(C) Iocrease ternperature and in domg extemal
work
(D) Inqease intemal energy a g (C) Reaction
(D) Splitting

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