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TN 12th Model Question Paper Microbiology

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TN 12th Model Question Paper Microbiology – Text

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Page 1

No. of Printed Pages : 8
1362 (NP)
!1362NPMicrobiology! £vÄ Gs
Register Number

PART - III
~sq°›¯À / MICROBIOLOGY
( uªÌ ©ØÖ® B[Q» ÁÈ / Tamil & English Version)

Põ» AÍÄ : 2.30 ©o ÷|µ® ] [ ö©õzu ©v¨ö£sPÒ : 70

Time Allowed : 2.30 Hours ] [ Maximum Marks : 70

AÔÄøµPÒ : (1) AøÚzx ÂÚõUPЮ \›¯õP £vÁõQ EÒÍuõ GߣuøÚ
\›£õºzxU öPõÒÍÄ®. Aa_¨£vÂÀ SøÓ°¸¨¤ß AøÓU
PsPõo¨£õÍ›h® EhÚi¯õPz öu›ÂUPÄ®.
(2) }»® AÀ»x P¸¨¦ ø©°øÚ ©mk÷© GÊxÁuØS®,
AiU÷PõikÁuØS® £¯ß£kzu ÷Ásk®. £h[PÒ ÁøµÁuØS
ö£ß]À £¯ß£kzuÄ®.
(3) ÷uøÁ¯õÚ Ch[PÎÀ £h[PÒ ÁøµP.
Instructions : (1) Check the question paper for fairness of printing. If there is any lack of
fairness, inform the Hall Supervisor immediately.
(2) Use Blue or Black ink to write and underline and pencil to draw diagrams.
(3) Draw diagrams wherever necessary.

£Sv & I / PART - I
SÔ¨¦ : (i) AøÚzx ÂÚõUPÐUS® Âøh¯ÎUPÄ®.
(ii) öPõkUP¨£mkÒÍ ©õØÖ ÂøhPÎÀ ªPÄ® Hئøh¯
Âøhø¯z ÷uº¢öukzxU SÔ±mkhß Âøh°øÚ²® ÷\ºzx
GÊuÄ®. 15x1=15
Note : (i) Answer all the questions.
(ii) Choose the most appropriate answer from the given four alternatives and
write the option code and the corresponding answer.

Page 2

1362 (NP) 2

1. RÌUPsh TØÔÀ Gx µõ£ºm PõUQØS ö£õ¸zu©õÚx AÀ» ?
(A) PõUQß öPõÒøPPøÍz ÷uõØÖÂzuõº
(B) uõß÷uõßÔ¯ uø»•øÓ ÷Põm£õmøh Bu›zuõº
(C) vh ÁͺFhPzøu ÁiÁø©zuõº
(D) ÷£êÀ»ì B¢uµõ]ì £õUj›¯õøÁ Psk¤izuõº
Which of the following statement is incorrect to Robert Koch ?
(a) Framed the Koch postulates
(b) Supported the spontaneous generation
(c) Formulated solid medium
(d) Identified Bacteria - Bacillus anthracis

2. ¤ßÁ¸ÁÚÁØÔÀ \›¯õP ö£õ¸¢v²ÒÍ Cønø¯ PshÔP.
(A) ö©ºUS›U S÷Íõøµk & Áõ² ~sq°º }UP®
(B) Gzv¼ß BUøék & J¼÷Põ øhÚªU ö\¯À£õk
(C) GzuÚõÀ & hÄÛ ªÀj²
(D) ]ÀÁº ø|m÷µm & ÷Põ÷ÚõPõUPÀ Ps öuõØÖ
Identify the correct matched pair from the following :
(a) Mercury chloride - Gaseous Sterilization
(b) Ethylene oxide - Oligodynamic action
(c) Ethanol - Downy Mildew
(d) Silver nitrate - Gonococcal eye infection

3. TØÖ (A) : ±ìm \õUP÷µõø©]ì ö\º÷Á]÷¯ vµõmø\ \õøµ J°ÚõP
ö|õvUP ö\´QÓx.
TØÖ (B) : PõØÓØÓ `Ì{ø» J°ß u¯õ›¨¤ØS \õuP©õP EÒÍx.
(A) TØÖ (A) &¯õÚx (B) &¯õÀ Bu›UP¨£kQÓx.
(B) TØÖ (B) &¯õÚx TØÖ (A) &ÂØS ö£õ¸zu©õÚx AÀ».
(C) TØÖ (A) ©mk÷© \›¯õÚx.
(D) TØÖ (B) uÁÓõÚx.
Statement (A) : Yeast Saccharomyces cerevisiae ferments grape juice into wine.
Statement (B) : Anaerobic condition favour the wine production.
(a) Statement (A) is supported by Statement (B).
(b) Statement (A) is not matched with Statement (B).
(c) Statement (A) alone is true.
(d) Statement (B) is false.

Page 3

3 1362 (NP)

4. ‰ßÓõÁx ]Qaø\ •øÓ°À, PÈÄ}›À EÒÍ £õ죵ø\ __________
£¯ß£kzv PõÀ]¯® £õì÷£mhõP Ą̃£iÁõQÓx.
(A) ysh¨£mh Põº£ß (B) S÷Íõ›ß Áõ²
(C) _snõ®¦ (D) A®÷©õÛ¯õ
In the tertiary treatment process of sewage, phosphorous is precipitated as calcium
phosphate by using __________.
(a) activated carbon (b) chlorine gas
(c) lime (d) ammonia

5. ¤ßÁ¸ÁÚÁØÔÀ \›¯õP ö£õ¸¢v²ÒÍ CønPøÍ PshÔP.
(i) EmöPõÒÐuÀ & Põ»µõ
(ii) Em_Áõ]zuÀ & i³£ºS÷Íõ]ì
(iii) §a]PÒ PizuÀ & AIDS
(iv) ¤Ó PhzxuÀ & ]L¤¼ì
(A) (ii), (iii), (iv) (B) (i), (ii), (iii)
(C) (i), (ii), (iv) (D) (i), (iii), (iv)
Which of the following pair is correctly matched ?
(i) Ingestion - Cholera
(ii) Inhalation - Tuberculosis
(iii) Arthropod bite - AIDS
(iv) Congenital - Syphilis
(a) (ii), (iii), (iv) (b) (i), (ii), (iii)
(c) (i), (ii), (iv) (d) (i), (iii), (iv)

6. ¸©õmiU Põ´a\¼À RÌÁ¸® G¢u BßiöáßPÒ öuõhº¦øh¯øÁ ?
(A) BÀ¦ªß (B) S÷Íõ¦¼ß
(C) L¨ÍõöáÀ¼ß (D) ø©÷¯õ]ß
Which of the following major antigen is involved in Rheumatic fever episodes ?
(a) Albumin (b) Globulin
(c) Flagellin (d) Myosin

7. §mh¨£mh uõøh, vjº vjöµßÖ ]›US® {ø» ©ØÖ® K¤ìz÷uõ÷hõÚõì
GßÝ® ©¸zxÁ AÔSÔPÒ G¢u ÷|õ²hß öuõhº¦øh¯x ?
(A) æöPÀ»õ]ì (B) i¨w›¯õ
(C) öhmhÚì (D) øhL£õ´k
To which disease, the clinical features of Lockjaw, Sporadic grin and Opisthotonos are
related ?
(a) Shigellosis (b) Diphtheria
(c) Tetanus (d) Typhoid

Page 4

1362 (NP) 4

8. ©ÛuÛÀ G¢u ¦Ê 10 Ai }Í® Áͺ¢x, 25 Á¸h[PÒ Áøµ ÁõÌ¢x
÷|õø¯ EshõUSQÓx ?
(A) L÷£]÷¯õ»õ (B) ]ìm÷hõ÷\õª¯õ
(C) ½è÷©Û¯õ (D) jÛ¯õ
Which worms grow upto 10 feet and live upto 25 years and cause disease in
humans ?
(a) Fasciola (b) Schistosomia
(c) Leishmania (d) Taenia

9. ¤Ó¨¦Ö¨¦ AÇØ], Áõ°À ö©ß£hºÄ, ÷uõÀ ©ØÖ® ~øµ±µÀ ÷|õ´PøÍ
EshõUS® EøÓ¯ØÓ Dìk __________ BS®.
(A) ©xöµÀ»õ ø©]÷hõ©õiì
(B) ÷Psihõ BÀ¤Pßì
(C) Q›¨÷hõPõUPì {÷¯õ£õº©ßì
(D) \õUP÷µõø©]ì ö\º÷Á]÷¯
Vaginitis, Oral thrush, Skin and Pulmonary infection are caused by
non-capsulated yeast _________.
(a) Madurella mycetomatis
(b) Candida albicans
(c) Cryptococcus neoformans
(d) Saccharomyces cerevisiae

10. G¢u öí¨£øhiì øÁµì ÁøP¯õÚx Áõ´&©»Áõ´ ÁȯõP £µÄQÓx ?
(A) C ©ØÖ® D (B) D ©ØÖ® G
(C) B ©ØÖ® C (D) A ©ØÖ® E
Which type of Hepatitis Virus are transmitted via faecal-oral route ?
(a) C and D (b) D and G
(c) B and C (d) A and E

11. __________ {n}º EÖ¨¤À ö\¼¯º ö\ÀPÒ EÒÍx.
(A) ÷uõÀ (B) ©spµÀ
(C) øu©ì (D) {n}º •ia_
__________ lymphoid organ contains nurse cells.
(a) Skin (b) Spleen
(c) Thymus (d) Lymph nodes

Page 5

5 1362 (NP)

12. Á¾ÁõÚ TØÖ (A) : IgM Gvºö£õ¸ÍõÚx £õUj›¯õ ©ØÖ® øÁµì
öuõØÖPμ¸¢x £õxPõ¨£Î¨£vÀ •UQ¯
£[S ÁQUQÓx.
Põµn® (R) : ÷|õ´z uk¨£õØÓ¼ß ysh¼À IgM
Gvºö£õ¸ÍõÚx •u¼À ÷uõßÖQßÓ •UQ¯
Gvºö£õ¸ÍõS®.
(A) (A) ©ØÖ® (R) &Cµsk® uÁÖ
(B) (A) &uÁÖ, (R) &\›
(C) (A) &\›, (R) &Gߣx (A) &ÂØPõÚ \›¯õÚ Põµn®
(D) (A) &\›, (R) &Gߣx (A) &ÂØPõÚ \›¯õÚ Põµn® CÀø»
Assertion (A) : IgM antibody plays an important role in the defense against
bacterial and viral diseases.
Reason (R) : IgM immunoglobulin is produced in early primary immune
response.
(a) Both (A) and (R) are false.
(b) (A) is false, (R) is true.
(c) (A) is true, (R) is the correct explanation of (A).
(d) (A) is true, (R) is not the correct explanation of (A).

13. ÁøP II ªøP Tº EnºÄ ÂøÚ __________ Gvº¨ö£õ¸ÒPÍõÀ
ö\¯»õUP¨£kQÓx.
(A) IgA1 AÀ»x IgD (B) IgE
(C) IgG AÀ»x IgM (D) IgA AÀ»x IgE
Type II hypersensitivity reaction are mediated by _________ antibodies.
(a) IgA1 or IgD (b) IgE
(c) IgG or IgM (d) IgA or IgE

14. ‰ßÖ {³UÎ÷¯õøhmPÒ ¦µuzvÀ EÒÍ __________ Aª÷Úõ Aª»zøu
{ºn°US®.
(A) 3 (B) 4 (C) 1 (D) 2
Three nucleotides codes for __________ amino acid in a protein.
(a) 3 (b) 4 (c) 1 (d) 2

15. ¤ßÁ¸ÁÚÁØÔÀ Gx •iÄ ÷Põhß ?
(A) CAG (B) AAG (C) UGA (D) GCU
Which of the following is a stop codon ?
(a) CAG (b) AAG (c) UGA (d) GCU

Page 6

1362 (NP) 6

£Sv & II / PART - II
GøÁ÷¯Ý® BÖ ÂÚõUPÐUS Âøh¯ÎUPÄ®. ÂÚõ Gs 24 &US Pmhõ¯©õP
Âøh¯ÎUPÄ®. 6x2=12
Answer any six questions. Question No. 24 is compulsory.
16. UÍõìm›i¯® öhmhøÚ&°ß GøÁ÷¯Ý® |õßS £s¦PøÍ GÊxP.
Write down any four characteristics of Clostridium tetani.
17. mµU÷Põ©õ GßÓõÀ GßÚ ? Auß ÷|õ´ Põµoø¯ GÊxP.
What is trachoma ? Give the causative agent.
18. y]¨£h»® GßÓõÀ GßÚ ?
What is aerosol ?
19. ø©]m÷hõ©õ GßÓõÀ GßÚ ?
What is mycetoma ?
20. ]m›U Aª»zvß H÷uÝ® Cµsk £¯ßPøÍU TÖP.
Write any two uses of Citric acid.
21. G¨¤÷hõ¨ & Áøµ¯Ö.
Define Epitope.
22. ö\¯ÀªS uøhPõ¨§mk & Áøµ¯Ö.
Define active immunization.
23. öáÚiU AÀ»x ©µ¦U÷Põm GßÓõÀ GßÚ ?
What is Genetic Code ?
24. G¢u •øÓ°ß ‰»® ¦v¯uõP u¯õ›UP¨£mh J¸ iìCßLö£Uhßm&ß
vÓøÚ PshÔ¯ •i²® ?
By which method the efficiency of newly formulated disinfectant is tested ?
£Sv & III / PART - III
GøÁ÷¯Ý® BÖ ÂÚõUPÐUS Âøh¯ÎUPÄ®. ÂÚõ Gs 33 &US
Pmhõ¯©õP Âøh¯ÎUPÄ®. 6x3=18
Answer any six questions. Question No. 33 is compulsory.
25. ÷í Põ´a\À GßÓõÀ GßÚ ?
What is Hay fever ?
26. ~sq°›¯À PØ£x Hß •UQ¯zxÁ® Áõ´¢ux ?
Why is the study of microbiology important ?
27. ¥mhõ öíº¨¤ì øÁµì GßÓõÀ GßÚ ? Euõµn® u¸P.
What are Beta herpes virus ? Give an example.

Page 7

7 1362 (NP)

28. } GÆÁõÖ E°ºÁÈ •øÓ°À uõÁµ[PøÍ uõUS® §a]PøÍ AȨ£õ´ ?
How will you kill the insects of plants in a biological way ?

29. ìmöµ¨÷hõPõUPì ø£÷¯õãßêÚõÀ HØ£k® \õuõµn ÷|õ´ öuõØÖ
©ØÖ® ö©ß v_UPÎÀ ~øÇ¢x uõUS® öuõØøÓ £mi¯¼kP.
List out the invasive soft tissue infection and non-invasive infection caused by
Streptococcus pyogenes.

30. HIV ÷|õ´z
öuõØÖ ukUP¨£k® •øÓPÒ ¯õøÁ ? GøÁ÷¯Ý®
‰ßÔøÚU TÖP.
What are the preventive measures of HIV ? (any three)

31. ÷£]À»› Á°ØÖUPk¨¦ ÷|õø¯ EshõUS® ~sq°› ¯õx ? ÷|õ°ß
AÔSÔPøÍ £mi¯¼kP.
Which micro-organism is responsible for bacillary dysentery ? List out the symptoms.

32. Eß ÃmiÀ APØÔ¯, ]øuÁøh¯U Ti¯ ö£õ¸ÒPøÍ } GÆÁõÖ
£¯ÝÒÍuõP ©õØÖÁõ´ ?
How do you convert the house-hold degradable waste substances into useful one ?

33. |a]À»õ |a_ÂØS®, E°¸ÒÍ uk¨§mk ö£õ¸ÐUS©õÚ ÷ÁÖ£õkPøÍ
GÊxP.
Write down the differences between the live vaccine and toxoid.

£Sv & IV / PART - IV
AøÚzx ÂÚõUPÐUS® Âøh¯ÎUPÄ®. 5x5=25
Answer all the questions.

34. (A) PÈÄ}º ]Qaø\ •øÓ°À G¢u ]Qaø\ •øÓUS E°›¯À ]Qaø\
•øÓ GßÖ AøÇUP¨£kQßÓx ? AvÀ Cµsk •øÓPøÍ ©mk®
›ÁõP GÊxP.
AÀ»x
(B) Aö»Uéõshº L¤Íª[PõÀ Psk¤iUP¨£mh E°º Gv› ö£õ¸Îß
öuõÈØ\õø» u¯õ›¨ø£ ÂÁ›UPÄ®.
(a) In sewage treatment, which method is called biological treatment method ? Explain
any two methods in detail.
OR
(b) Describe the industrial production of antibiotic discovered by Alexander Fleming.

Page 8

1362 (NP) 8

35. (A) PvºÃaø\U öPõsk GÆÁõÖ ~sq°›PÒ Pmk¨£kzu¨£kQßÓÚ ?
AÀ»x
(B) JÎø¯ £¯ß£kzuõ©À G¢u ~s÷nõUQ ö\À¼ß ~s Aø©¨¤øÚ
EØÖ÷|õUP £¯ß£kzu¨£kQßÓx ? A¢~s÷nõUQ°À EÒÍhUQ²ÒÍ
Ai¨£øh £iPÒ ¯õøÁ ?
(a) How will you control micro-organisms using Radiation ?
OR
(b) Which is the most advanced microscope to observe the fine structure of cells
without using light source ? What are the basic steps involved in it ?

36. (A) PõºÛ£õUj›¯® i¨w›÷¯Âß ÷|õ´ uk¨¦ ÁÈ •øÓø¯ ÂÁ›UPÄ®.
AÀ»x
(B) UÍõªi¯õÂß CÚ¨ö£¸UP® £ØÔ ÂÁ›UPÄ®.
(a) Describe the prophylaxis of Corynebacterium diphtheriae through flow chart.
OR
(b) Describe the reproduction in Chlamydia.

37. (A) jÛ¯õ ÷\õ¼¯® £h® Áøµ¢x Auß ÁõÌUøPa _ÇØ]ø¯ GÊxP.
AÀ»x
(B) ø»® ÷|õ°ß {ø»PøÍ ÂÁ›UPÄ®.
(a) Draw Taenia solium and discuss about its life cycle.
OR
(b) Write about the clinical manifestations of lyme disease.

38. (A) Gvºö£õ¸Îß ÁøPPÒ ¯õøÁ ? AÁØÔß £oPøÍ £mi¯¼kP.
AÀ»x
(B) Bªì ÷\õuøÚø¯ £¯ß£kzv } GÆÁõÖ, ÷Áv¨ö£õ¸Ò, Põß\º
Esk £sq©õ Gߣøu Psk¤i¨£õ´ ?
(a) What are the different types of antibodies ? List out the functions of it.
OR
(b) How will you identify chemical carcinogen using Ames test ?

- oOo-

Document Details

Board / OrgTamil Nadu Board
ExamClass 12
TypeSample Paper
Pages8
Updated22 Jul 2026