CBSE Class 12 Sample Paper 2026 for Medical Diagnostics

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SAMPLE
PAPER
2026

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CBSE | DEPARTMENT OF SKILL EDUCATION
MEDICAL DIAGNOSTICS (SUBJECT CODE - 828)
Blue-print for Sample Question Paper for Class XII (Session 2025-2026)

Max. Time: 3 Hours Max. Marks: 60

PART A - EMPLOYABILITY SKILLS (10 MARKS):

OBJECTIVE SHORT
UNI TOTAL
NAME OF THE UNIT TYPE ANSWER
T QUESTIONS TYPE QUESTIO
NO. QUESTIONS NS
1 MARK EACH 2 MARKS
EACH
1 Communication Skills - IV 1 1 2
2 Self-Management Skills - IV 1 1 2
Information and Communication
3 2 1 2
Technology Skills - IV
4 Entrepreneurial Skills - IV 1 1 2
5 Green Skills - IV 1 1 2
TOTAL QUESTIONS 6 5 11
NO. OF QUESTIONS TO BE Any 4
Any 3 07
ANSWERED
TOTAL 1x4=4 2x3=6 10
MARKS MARKS

PART B - SUBJECT SPECIFIC SKILLS (50 MARKS):

DESCRIPTIV
OBJECTIV SHORT SHORT
E/LONG
E TYPE ANS.TYPE ANS.TYPE
UNI ANS. TYPE TOTAL
NAME OF THE QUESTIO QUES.-I QUES.- II
QUESTIONS
T NS QUESTIO
UNIT
NO. 1 MARK 2 MARKS 3 MARKS NS
4 MARKS
EACH EACH EACH
EACH
1 Hematology Lab 11 2 1 1 15

2 Blood Bank 1
10 2 2 15
and
Transfusion
3 Cytopathology 11 1 1 2 15

TOTAL QUESTIONS 32 5 3 5 45
NO. OF QUESTIONS
26 Any 3 Any 2 Any 3 34
TO BE ANSWERED
TOTAL MARKS 1 x 26= 2x3=6 3x2=6 4 x 3 = 12 50
26 MARKS

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MEDICAL DIAGNOSTICS (SUBJECT CODE - 828)
SAMPLE PAPER FOR CLASS XII (SESSION 2025-2026)
Max. Time: 3 Hours Max. Marks: 60
General Instructions:
1. Please read the instructions carefully.
2. This Question Paper consists of 24 questions in two sections – Section A & Section B.
3. Section A has Objective type questions whereas Section B contains Subjective type questions.
4. Out of the given (6 + 18 =) 24 questions, a candidate has to answer (6 + 11 =) 17 questions
in the allotted (maximum) time of 3 hours.
5. All questions of a particular section must be attempted in the correct order.
6. SECTION A - OBJECTIVE TYPE QUESTIONS (30 MARKS):
i. This section has 06 questions.
ii. There is no negative marking.
iii. Do as per the instructions given.
iv. Marks allotted are mentioned against each question/part.
7. SECTION B – SUBJECTIVE TYPE QUESTIONS (30 MARKS):
i. This section contains 18 questions.
ii. A candidate has to do 11 questions.
iii. Do as per the instructions given.
iv. Marks allotted are mentioned against each question/part.
SECTION A: OBJECTIVE TYPE QUESTIONS
Q.
QUESTION Marks
No.
Q. 1 Answer any 4 out of the given 6 questions on Employability Skills (1 x 4 = 4 marks)
i. is not a stage of active listening 1
a) Remembering
b) Responding
c) Respecting
d) Receiving
ii. What does S signify in SMART? 1
iii. What is the format of writing any function? 1
iv. Define creativity. 1
v. Which of the following is an example of electric vehicle technologies hybridized with 1
fossil fuel engines
(a) Battery cars
(b) Automatic vehicles
(c) PHEVs(Plug-in Hybrid Electric Vehicles)
(d) EEVs (Energy Efficiency Vehicles)
vi. is used to find the average of numbers in a range of cell. 1
Q. 2 Answer any 5 out of the given 7 questions (1 x 5 = 5 marks)
i. Write down the full form of CBC. 1
a) Common blood count
b) Complete blood count
c) Complete bone count
d) Cytopatholgical blood count

ii. Name the anticoagulant that is best to use for coagulation studies. 1

iii. What do you mean by MCHC? 1

iv. The purpose of using Glycerin for observing blood smear is- 1
a) Inhibting growth of micro organisms
b) To make RBC settle on surface of counting chamber
c) To inhibit rouleaux formation
d) To stain nuclei of leukocytes.
2

v. In which condition decreased osmotic fragility is seen? 1
a) Congenital spherocytosis
b) Thalassemia
c) Autoimmune disorders
d) Cushing’s disease
vi. Write down the full form of PCV. 1

vii. Name the instrument to separate solution into sediment and supernatant by using 1
required speed.

Q. 3 Answer any 6 out of the given 7 questions (1 x 6 = 6 marks)
i. Name one commonly used method to measure ESR. 1
a) Benedict’s test method
b) Fehling’s test method
c) Westergren’s Method.
d) Romanowsky Method
ii. Reference range for calculating RBC count in females is - 1
a) 3.8-4.8 millions/cumm
b) 4.5-5.5 millions/cumm
c) 2.8-3.8 millions/cumm
d) 4.8-5.8 millions/cumm
iii. Which RBC diluting fluid is used if one wants to prevent rouleaux formation? 1

iv. What do you mean by Hematopoiesis? 1
a) An increase in platelet count
b) Production of blood cells
c) An increase in WBC count
d) An increase in RBC count
v. Who discovered Rhesus blood group system? 1

vi. The titer of an antibody is usually determined by testing two fold serial dilution of the 1
serum against selected cells.

vii. Rh antibody titres are done in the antenatal period - 1
a) Rh positive mother with Rh positive foetus may get alloimmunised with anti D
and cause hemolytic disease
b) Rh positive mother with Rh negative foetus may get alloimmunised with anti D
and cause hemolytic disease
c) Rh negative mother with Rh negative foetus may get alloimmunised with anti
D and cause hemolytic disease
d) Rh negative mother with Rh positive foetus may get alloimmunized with anti D
and cause hemolytic disease
Q. 4 Answer any 5 out of the given 6 questions (1 x 5 = 5 marks)
i. is defined as clumping of particles that have antigen on their surface and 1
is brought about by anti-bodies.
a) Agglutination
b) Hemolysis
c) Reaction
d) Blood clot
ii. Which is the largest component of Biomedical Waste generated- 1
a) Radioactive waste
b) Hazardous waste
c) Non hazardous waste
d) Infectious waste.
iii. are serum proteins, more specifically immunoglobulins. 1
a) Antigens
b) Antibodies
c) Pathogen
d) Haemocytes

3

iv. Romit has a platelet count of 104,000/microliter in his blood. He is suffering from 1
condition called-

v. What are the antigens of the Lutheran system? 1
a) Lu m and Lu n
b) Lu c and Lu d
c) Lu a and Lu b
d) Lu u and Lu v

vi. The two types of processes which can be done using a cell separator are- 1
a) Continuous and discontinuous flow processes
b) Continuous and interrupted flow processes
c) Controlled and uncontrolled flow processes
d) Balanced and unbalanced flow processes.
Q. 5 Answer any 5 out of the given 6 questions (1 x 5 = 5 marks)

i. What is the basic function of autoclave in laboratory? 1

ii. Exfoliative cytology does not deal with study of cells from 1
a) Epithelial and Mesothelial lining
b) Body fluids
c) Tissue fragments extracted from lesions
d) Bronchial washings and buccal smear
iii. Name one special purpose fixative used in a cytology laboratory. 1
a) AAF fixative
b) Carnoy’s fixative
c) Formalin
d) Giemsa stains
iv. The preferred test for detecting cervical cancer is- 1
a) RT PCR
b) ELISA
c) PAP Smear
d) WIDAL Test
v. Name the chemical which is used for dehydration process. 1

vi. What do you mean by Cytology? 1

Q. 6 Answer any 5 out of the given 6 questions (1 x 5 = 5 marks)

i. Write down full form of FNAC. 1
a) Fine needle aspiration cytology
b) Free needle aspiration cytology
c) Fine needle activation cytology
d) Free needle activation cytology

ii. is used strictly for taking materials from endocervix. 1
a) Endo-cervical brush
b) Exo-cervical brush
c) Endo-cellular brush
d) Extracellular brush

iii. It is important that no air-drying occurs prior to -. 1
a) Fixation
b) Dehydration
c) Clearing
d) sterilizing

4

iv. 1

Identify the given instrument-
a) Cryopreservative bath
b) Plasma thawing bath
c) Cytospin
d) Platelet agitator

v. Name one routine fixative that was originally recommended by Papanicolaou. 1

vi. Cell blocks are made from 1
a) all fluid aspirates
b) all epithelial tissues
c) tissue from lumps and lesions
d) reticulocyte cells

5

SECTION B: SUBJECTIVE TYPE QUESTIONS
Q.
QUESTION Marks
No.
Answer any 3 out of the given 5 questions on Employability Skills in 20 – 30 words each (2 x
3 = 6 marks)
Q. 7 Describe any 2 steps of active listening? 2

Q. 8 Give any two of Big Five factors of personality. 2

Q. 9 Entrepreneurship is considered to be both an art and a science. Why? 2

Q. 10 Mention any two ways of minimizing waste and pollution. 2

Q. 11 Differentiate between a worksheet and a workbook. 2

Answer any 3 out of the given 5 questions in 20 – 30 words each (2 x 3 = 6 marks)

Q. 12 Write down the advantages of Evacuated Tube System. 2

Q. 13 Give the principle of Sahli’s method used for haemoglobin estimation. 2

Q. 14 Write down the importance of blood storage cabinets. 2

Q. 15 Explain two types of materials used to detect respiratory tract malignancies. 2

Q. 16 2

Differential leukocyte count is done to estimate the percentage of different types of
WBC’s in blood. What are the various sources of error while performing a differential
count.
Answer any 2 out of the given 3 questions in 30– 50 words each (3 x 2 = 6 marks)

Q. 17 Enumerate three stages of the ESR experiment. 3

Q. 18 What are the different types of blood collection bags used in blood banks? Describe 3
the role of tube sealer while collecting blood in bags.

Q. 19 Enlist the indications of FNAC. Outline its methodology. 3

Answer any 3 out of the given 5 questions in 50– 80 words each (4 x 3 = 12 marks)

Q. 20 How can the microscope be handled properly in the laboratory? 4
Q. 21 How can the bleeding time be measured by IVY method? 4
Q. 22 Reema is working in the cytology laboratory of a reputed hospital. What kind of 4
safety rules shall be followed by her in the laboratory?

Q. 23 Describe in detail any four sampling devices used by professional medical personnel 4
for preparation of FGT smear.
Q. 24 Enumerate the functions of four special purpose fixatives 4

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Study Materials
Notes

Model Papers Class 6 Notes

Sample Papers Class 7 Notes
Half Yearly Sample Papers Class 8 Notes

Class 9 Notes
Important Resources
Class 10 Notes
Periodic Table
Class 11 Notes
Writing Skills / Formats

Maps of India / World Class 12 Notes

Books and Solutions

NCERT Books
NCERT Book Solutions
HC Verma Chapter Wise Solutions
RD Sharma Solutions
CGBSE Solutions