CBSE Class 12 Question Paper 2026 Medical Diagnostics

FOR CBSE CLASS 12 EXAM PREPARATION

CBSE Class 12 2026
Question Paper ·
Medical Diagnostics
EXAM YEAR TYPE SUBJECT

CBSE Class 12 2026 Question Paper Medical Diagnostics

Notes · Sample Papers · Previous Year Papers · Mock Tests

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a SET-4
Series : SR3PQ - 
Q.P. Code 352
 .  -   - 
Roll No. -    
Candidates must write the Q.P. Code
on the title page of the answer-book. m
m .co
.co s e m
s em   l a
g a
l MEDICAL DIAGNOSTICS ag
a
  : 3    : 60
Time allowed : 3 hours Maximum Marks : 60

       -    24  
-        -    -  -   


       -  24    .co
m
m
        s,e-        
gla

 

a
 -     15        -     10.15
    10.15   10.30     -      
  -      
 Please check that this question paper contains 24 printed pages.
 Q.P. Code given on the right hand side of the question paper should be written
on the title page of the answer-book by the candidate.
m
m Please check that this question paper contains 24 questions.
c. o Please write down the serial number of the question sinem
 the answer-
.co
s em book at the given place before attempting it. gla
la  15 minute time has been allotted to read this question
a paper. The question
ag paper will be distributed at 10.15 a.m. From 10.15 a.m. to 10.30 a.m., the
candidates will read the question paper only and will not write any answer
on the answer-book during this period. {}
352 * 2410 1 P.T.O.

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a For more Question Papers, Sample Papers, Notes & Syllabus visit Page 1 of 24

  :

(i)    
  

(ii)  -  24          : -  - 

(iii) -        -        

(iv)   (6 + 18) = 24   ,   3    ()  
(6 + 11) = 17      

(v)                 

(vi) - :     (30 ) :

(a)    6   

(b)          

(c)      

(d)       

(e)  /          

(vii) - :     (30 ) :

(a)    18   

(b)   11    

(c)       

(d)  /          

352 * 2 {}

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General Instructions :
a
(i) Please read the instructions carefully.

(ii) This Question Paper consists of 24 questions in two sections : Section–A
& Section–B.

(iii) Section–A has Objective type questions, whereas Section–B contains
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Subjective type questions.
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(iv) Out ofm
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+ 11) = 17 questions in the allotted (maximum) time of 3 hours. ag
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(v) All questions of a particular section must be attempted in the correct
order.

(vi) Section–A : Objective Type Questions (30 Marks) :

(a) This Section has 6 questions.

(b) m
It is mandatory for every student to complete all the questions as
per instructions.
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(c) There is no negative marking.
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a given.
(d) Do as per the instructions

(e) Marks allotted are mentioned against each question/part.

(vii) Section–B : Subjective Type Questions (30 Marks) :

(a) This Section contains 18 questions.

(b) A candidate has to do 11 questions.
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(c) Do as per the instructions given.

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(d) Marks allotted are mentioned against each question/part.
las a g
ag

352 * 3 {}

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a For more Question Papers, Sample Papers, Notes & Syllabus visit Page 3 of 24

 – 
(   )

1.      6     4     41=4

(i)    ________     1

(A)  

(B)  

(C)  

(D)  

(ii)          -       
___________  /   1

(A) 

(B) 

(C) -

(D) 

(iii)      FFM      ? 1

(iv) _________    ,        1

(A)  (B) 

(C)  (D) 

352 * 4 {}

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SECTION – A
a
(Objective Type Questions)

1. Answer any 4 out of given 6 questions on Employability Skills. 41=4

(i) Every effective communication starts with ________. 1

m
(A) listening
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(B) reading
s l a
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(D) speaking

(ii) To achieve goals, one must always set a ___________ to get the job

done within a specified time limits. 1

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(A) areas
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(B) plans
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(C) deadlines

(D) standards

(iii) What do you understand by FFM in relation to personality disorder ? 1

(iv) A _________ is a rectangle shaped box, where the rows and columns m
m .co
m .co meet.
s e m 1

s e g l a
g la (A) column (B) grid a
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(C) formula (D) cell

352 * 5 {}

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a For more Question Papers, Sample Papers, Notes & Syllabus visit Page 5 of 24

(v)       ________   ___________      1

(vi)   -    ? 1

2.   7     5     51=5

(i)             

              ? 1

(A)   (B)  

(C)   (D)  

(ii)           ? 1

(A)   (B) 

(C)   (D)   

(iii)       ? 1

(A)    

(B)   

(C)   

(D)   

352 * 6 {}

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m
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m .co s em
se g la
a
(v) Self-doubt comes when we do not have confidence in ________ and

our ___________. 1

(vi) What is roof top rainwater harvesting ? 1

m
c o m m .co
2. Answer any 5 .out of the given 7 questions. 5  1 = 5 se
s em g l a
a
(i) gAl thick blood film is required to detect parasites like microfilaria anda
a
malaria parasites. _____ is used for staining thick blood films. 1

(A) Field’s stain (B) Giemsa stain

(C) Wright’s stain (D) Leishman’s stain

o m
. c
(ii) Which equipment is needed for haemoglobin estimation ? 1
e m
s
(A) Blood donor couch la
ag
(B) Haemoglobinometer

(C) Blood bags (D) Blood collection bags

(iii) What do you mean by diagnostic cytopathology ? 1

(A) Interpretation of exfoliative cells.
m
m .co
.co
(B) Interpretation of organs.
e m
e m l as
las (C) Interpretation of muscles.
ag
ag
(D) Interpretation of nerves.

352 * 7 {}

m .
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g la ag
a For more Question Papers, Sample Papers, Notes & Syllabus visit Page 7 of 24

(iv)               
()      ? 1

(A)  (B) 

(C)  (D)   

(v)               ? 1

(A) -  (B) - 

(C) -  (D) - 

(vi) DNA       ? 1

(A) 6 (B) 4

(C) 2 (D) 1

(vii)    , _____           

         1

(A)   (B)  

(C)   (D)  

3.   7     6     61=6

(i) LEWIS         : _____ 1

(A) Fy a  Fy b (B) JK a  JK b

(C) Le a  Le b (D)  M   N
352 * 8 {}

For more Question Papers, Sample Papers, Notes & Syllabus visit Page 8 of 24

m
m .co

m .co s e m
se g l a
a
(iv) Which instrument separates a solution or mixture into sediment and
supernatant using the required speed ? 1

(A) Microscope

(B) Centrifuge

m
.co
(C) Hemocytometer
m
.co
(D) Automated cell counters
e m
s
(v) In the emprocess of pap smear test _____ of cervix is chosen to collect glas
g la a 1
a the sample.

(A) neuro-muscular junction

(B) squamo-columnar junction

(C) epithelial-squamo junction

(D) epithelial-columnar junction
m
(vi) DNA is composed of how many nitrogen bases ?
.co
m (B) 4
1

(A) 6 s e
g la
(C) 2 a (D) 1

(vii) While preparing the blood smear, a _____ should be displayed with a
gradual transition from thick to thin areas and with no deformities. 1

(A) homogeneous spread (B) heterogeneous spread

(C) uneven spread (D) discontinuous spread
m
m
c.3.o Answer any 6 out of given 7 questions. .co
s em 61=6

s em g la
l a (i) LEWIS blood group system contains two antigens _______.
a 1

ag (A) Fy a and Fy b (B) JK a and JK b

(C) Le a and Le b (D) Anti M and Anti N
352 * 9 {}

m .
.co s e m
s em l a
g la ag
a For more Question Papers, Sample Papers, Notes & Syllabus visit Page 9 of 24

(ii)    -              ? 1

(A)    (B)   
(C)    (D)   

(iii)   _____    ,       1

(A)  (B) 
(C)  (D) 

(iv) ,             ? 1

(A) IgA (B) IgM

(C) IgE (D) IgG

(v) _____ :             1

(A)     (B)    
(C)     (D)    

(vi)   _____  ,          1

(A)  (B) 
(C)  (D) 

(vii) FNAC  , -   _____       1

(A)  
(B)  
(C)   
(D) --

352 * 10 {}

For more Question Papers, Sample Papers, Notes & Syllabus visit Page 10 of 24

m
m .co

m .co s em
se g la
a
(ii) Name the test performed for early detection of cervical cancer at the
pre-invasive stage. 1
(A) Lipid profile test
(B) Pap smear test
(C) Kidney function test
m
(D) Abdominal ultrasonography
m .co
.co
(iii) _____ released in blood convert prothrombin to thrombin. 1
s e m
s em l a
gl(C)a Fibrinogen
(A) Thromboplastin (B) Thrombokinase
ag
a (D) Fibrin
(iv) Name the antibody that develops due to immunization following
pregnancy, previous transfusion or deliberate injection of
immunogenic material. 1
(A) IgA (B) IgM
(C) IgE
o m (D) IgG
c
. cytology or by bronchoscopic
(v) _____ can be detected mainly by sputum
e m
material.
las 1

ag
(A) Urinary tract malignancies
(B) Gastrointestinal tract malignancies
(C) Respiratory tract malignancies
(D) Reproductive malignancies
(vi) Acidic substances are _____ and so stain with basic dye. 1
m
.co
(A) hydrophilic (B) basophilic
m
m .co (C) hydrophobic
em
(D) acidophilic
s
s e g a stain.
(vii) In FNAC process, Air-dried smears are stained withl______ 1

g la (A) Papanicolaou stain
a
(B) Supra-vital stain
a
(C) Hematoxylin and eosin (D) May-Grunwald-Giemsa

352 * 11 {}

m .
.co s e m
s em l a
g la ag
a For more Question Papers, Sample Papers, Notes & Syllabus visit Page 11 of 24

4.   6     5     51=5

(i)                   
 ? 1

(A)   (B)  
(C)   (D) - 

(ii)     ()    ,     
             
     1

(A) 95  (B)   
(C)  (D)  

(iii) _____                
 ,   ,         1

(A)  (B) 
(C)  (D) 

(iv)           ? 1

(A)  (B) 
(C)  (D) 

(v)     -      ? 1

(A)  G, EA-50   
(B)   
(C)    
(D)   

352 * 12 {}

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m
m .co

m .co s e m
se g l a
4. Answer any 5 out of the given 6 questions.
a 51=5

(i) The blood storage cabinet is provided with some compartments
having special character doors. What is the special character of the
door of the blood storage cabinet ? 1

(A) transparent plexiglass (B) opaque wooden
m
c o m
(C) opaque plastic (D) translucent plastic
m .co
(ii) It is an. excellent fixative, but it is not used in most of the s e
e m l a
as
laboratories
l because of its safety hazards, odour and hygroscopic g
a
agnature. Identify the cytological fixative. 1

(A) 95% ethanol (B) Ether alcohol mixture

(C) Propanol (D) Denatured alcohol

(iii) _______ is the count higher than the reference range of platelets. It is
seen in iron deficiency anemia, after trauma, essential
m
.co
thrombocythemia etc. 1

(A) Leukopenia
e m (B) Thrombocytopenia
(C) Leukocytosis l as (D) Thrombocytosis
ag
(iv) By nature, antibodies are serum _______. 1

(A) Proteins (B) Lipids

(C) Glucose (D) Enzymes

(v) While performing the Giemsa stain procedure, which solutions are
used ? 1

m . com
c. o
(A) Orange G, EA 50 and Harris’s Hematoxylin
e m
em (B) Hematoxylin and Eosin
l as
las ag
ag (C) Giemsa and Distilled water

(D) Hematoxylin and Giemsa

352 * 13 {}

m .
.co s e m
s em l a
g la ag
a For more Question Papers, Sample Papers, Notes & Syllabus visit Page 13 of 24

(vi) CBC      ? 1

(A)    
(B)    
(C)   
(D)   

5.   6     5     51=5

(i)               ? 1

I.       
II.       
III.         
(A) I  II (B) II  III

(C) I  III (D) I, II  III

(ii)                ? 1

(A)   (B) 
(C)  (D) 

(iii)           ? 1

(A) ABO   

(B) Le a  Le b 

(C) JK a  JK b 

(D) Lu a  Lu b 

352 * 14 {}

For more Question Papers, Sample Papers, Notes & Syllabus visit Page 14 of 24

m
m .co

m .co s e m
se g l a
(vi) Full form of CBC is _______.
a 1

(A) Continuous Bone Marrow Count

(B) Complete Bone Marrow Count

(C) Continuous Blood Count

(D) Complete Blood Count m
m .co
.co s e m
5.
s
Answer any em5 out of given 6 questions. g a
5  1 =l5
l a
(i) gTo maintain safety in the laboratory which of the following methods
a
a
should be obtained ? 1

I. Proper disposal of hazardous wastes.

II. Pipette samples with mouth.

III. Laboratory coats must be worn by laboratory personnel at all
times. m
(A) I and II
.co
m (B) II and III
e
s (D) I, II and III
l a
ag
(C) I and III

(ii) Which type of cell helps to produce blood cells in the process of
hematopoiesis ? 1

(A) Bone marrow (B) Hematic

(C) Blood (D) Hematopoietic

(iii) The reciprocal relation between _____ is called Landsteiner’s law. m 1
m c. o
m .co (A) ABO antigens and antibodies
s e m
s e (B) Le a and Le b antigens
g l a
g la a
a (C) JK a and JK b antigens

(D) Lu a and Lu b antigens

352 * 15 {}

m .
.co s e m
s em l a
g la ag
a For more Question Papers, Sample Papers, Notes & Syllabus visit Page 15 of 24

(iv)           1

(A)  (B) 
(C)  (D) 

(v)           ? 1

(A)   (B)  
(C)   (D)   

(vi)  B+     B+            
      ? 1

(A) O+  B+ (B) A+  AB+

(C) A–  AB– (D) A+  AB–

6.   6     5     51=5

(i)               
   ,     ? 1

(A)  
(B)       
(C)    
(D)  

(ii)            -  
  ? 1

(A)  (B) 
(C)  (D) 

(iii) _____   -     1

(A)  (B) 
(C)  (D) 
352 * 16 {}

For more Question Papers, Sample Papers, Notes & Syllabus visit Page 16 of 24

m
m .co

m .co s e m
se g l a
a
(iv) Name one clearing agent used in laboratory. 1

(A) Formalin (B) Water

(C) Xylene (D) Alcohol

(v) Packed cell volume is measured by _____method. 1

(A) Wintrobe’s (B) Sahli’s
m
c o m
(C) Colorimetric (D) Acid Hematin
m .co
(vi) A manm
. s e
s e with B blood group marries a woman with B blood group.
+
l
g1 a +

l a
Which blood group will their child possess ? a
ag(A) O or B + + (B) A or AB + +

(C) A– or AB– (D) A+ or AB–

6. Answer any 5 out of given 6 questions. 51=5

(i) Name the record in the blood bank where the reports and the
m
.co
investigation for all transfusion adverse reaction are maintained. 1

(A) Issue register s em
g lakits and reagents used
a
(B) Register for diagnostic

(C) Transfusion adverse reaction reports

(D) Blood donor record

(ii) In the bone marrow, under the influence of _____, the committed
stem cells divide and differentiate into pro-erythroblast. 1

(A) reticulocyte (B) erythrocyte m
m .co
m .co (C) erythropoietin
s
(D) erythroblast
e m
s e l a
(iii) It is important that no air-drying occurs prior to _____.
g 1

g la (A) Fixation
a
(B) Dehydration
a
(C) Clearing (D) Embedding

352 * 17 {}

m .
.co s e m
s em l a
g la ag
a For more Question Papers, Sample Papers, Notes & Syllabus visit Page 17 of 24

(iv)    : (intrinsic)          
      ? 1

(A)   (B) ...

(C) ... (D)  

(v) FNAC      ? 1

(A)    

(B)    

(C)    

(D)    

(vi) 1900  ABO           ? 1

(A)  (B)  

(C)   (D)   

-
(   )

     5     3   20-30     32=6

7.         2

8.        ? 2

9.       ?      2

352 * 18 {}

For more Question Papers, Sample Papers, Notes & Syllabus visit Page 18 of 24

m
m .co

m .co s em
se g la
a
(iv) Name the screening test to measure the efficiency of all stages of

intrinsic pathway of blood coagulation. 1

(A) Clotting time (B) KFT

(C) LFT (D) Bleeding time
m
(v)
c o m
What is the full form of FNAC ? 1
m .co
m . needle aspiration cytology s e
(A) Fine
s e l a
g a
l Free needle aspiration cytology
(B) ag
a
(C) Fine needle activation cytology

(D) Free needle activation cytology

(vi) Name the scientist who discovered the ABO Blood group antigens in

1900.
om
1

. c(B) Alexander Fleming
(A) Landsteiner
e m
las
(C) Louis Pasteur
ag (D) Watson and Crick

SECTION – B
(Subjective Type Questions)
Answer any 3 out of the given 5 questions on Employability Skills in
20-30 words each. 32=6
o m
m . c
c.7.o Name any four communication barriers. s e m 2
s em g l a
l a What do you understand by personality development ?a
ag
8. 2

9. What is formatting in spreadsheets ? Give any two examples. 2

352 * 19 {}

m .
.co s e m
s em l a
g la ag
a For more Question Papers, Sample Papers, Notes & Syllabus visit Page 19 of 24

10. -      2

11.           2

  5     3   20-30     32=6

12.    (Erythrocyte sedimentation rate)     
   2

13.             ? 2

14.    (Evacuated Tube System)     ? 2

15.        -        ? 2

16.                  ? 2

  3     2   30-50     23=6

17.             ? 3

, , -  ,  

18. ABO            3

19.             3

352 * 20 {}

For more Question Papers, Sample Papers, Notes & Syllabus visit Page 20 of 24

m
m .co

m .co s e m
se g l a
a
10. Write the contribution of non-technical entrepreneurs. 2

11. Give any four examples related to Green workers services. 2

Answer any 3 out of the given 5 questions in 20-30 words each. 32=6 m
m .co
.co
12. Enumerate the factors influencing the Erythrocyte sedimentation rate. 2
s e m
s em l a
la collection monitor play an important role in a blood bank ?
13. Howgblood ag 2
a
14. What are the advantages of the Evacuated Tube System ? 2

15. How is the endo-cervical brush used to examine the whole cervix ? 2

m
.co
16. To store the blood in blood bank, write down the role of platelet agitator
m
and incubator.
s e 2

g la
a
Answer any 2 out of the given 3 questions in 30-50 words each. 23=6

17. What result can we find out from papanicolaous stain for the following
elements ?

Nuclei, Cytoplasm, Non-keratinizing squamous cells, Keratinizing cells. 3
m
m .co
.co e m
18. Explain Landsteiner’s law in respect to ABO blood group system.
s
3

s em g l a
g la 19. Enumerate the problems encountered during the staining
a method of blood
a
smear. 3

352 * 21 {}

m .
.co s e m
s em l a
g la ag
a For more Question Papers, Sample Papers, Notes & Syllabus visit Page 21 of 24

  5     3   50-80     3  4 = 12
20.       (blood clotting mechanism)     
        4

21.        - (in vitro)  ,    4

22.               4

23.                
  4

24.                
   4

____________

352 * 22 {}

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m
m .co

m .co s em
se g la
a
Answer any 3 out of the given 5 questions in 50-80 words each. 3  4 = 12

20. Write a short note about the blood clotting mechanism and draw a flow
chart to show the steps. 4

21. Discuss about the antigen-antibody reactions that can occur in vitro. 4 m
m .co
m .co s e m
e
22. Define routine cytological fixatives and explain any three of them.
s l4a
g l a ag
a
23. Write down the working principle of the microscope used to study blood
cells. 4

24. List down the general guidelines to be kept in mind for storage and
archival in a pathology laboratory. 4

__________. c om
e m
las
ag

m
m .co
m .co s e m
s e g l a
g la a
a

352 * 23 {}

m .
.co s e m
s em l a
g la ag
a For more Question Papers, Sample Papers, Notes & Syllabus visit Page 23 of 24

352 * 2410 24 {}

For more Question Papers, Sample Papers, Notes & Syllabus visit Page 24 of 24